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EnVision 多标记微孔板检测仪

使您的研究踏上高速轨道:使用 Envision® 可更快速地引领发现

现在您再也不必在基于过滤器的系统的灵敏度与光栅的灵活性之间进行选择,PerkinElmer 可在单一系统中同时提供上述两种功能。使用 EnVision™ 多标记微孔板检测仪平台,您可在检测技术与应用之间轻松地进行切换,从而获得更佳的先导化合物检测性能。

PerkinElmer 了解什么对您才是最重要的:速度、灵敏度和灵活性。现在,您可在一个平台中获得胜过市场中其它台式检测仪的所有功能。在所有主要应用中,EnVision® 可读取所有的非同位素检测技术,包括荧光强度、荧光偏振、时间分辨荧光 (TRF)、化学发光、吸光度和Alphascreen。

两种选择,多种配件

EnVision® 系列产品目前包括两种仪器:EnVision®(装备快速的双检测器)以及 EnVision® Xcite(装备单检测器)。这两种仪器都配有标记专用光学镜模块、高能闪烁氙灯和高速检测器。同时已对载板架进行了优化以达到最快速度,它们还具有强大的并行功能和快速的物理运动性能。EnVision® 仪器可灵活方便地集成到全自动工作站系统中,旨在提供最大的配置灵活性,包括可以使用 1 到 3456 孔微孔板。当然,只有 EnVision® 才能提供可满足您未来需求的升级能力。

广泛的升级配件

无论您是选择 EnVision® 还是 EnVision® Xcite,都可以满足您的实验室目前和未来逐步升级的需求。这是因为 EnVision 是唯一可连续升级的多标记检测仪平台。有选择广泛的配件,包括::

  • 四重光栅
  • AlphaScreen
  • TRF 激光器
  • 增强的化学发光检测
  • 双通道加样器
  • 温度控制
  • 微孔载板架

选择 EnVision® 可获得比市场上大多数常用台式检测仪更高的灵敏度和无与伦比的速度。

Features

EnVision®EnVision® Xcite
Fast Dual DetectorAffordable Single Detector
In the past, you've had to compromise when choosing an instrument. The EnVision® Multilabel Plate Reader delivers speed and flexibility-without sacrificing the sensitivity so crucial to your research.
  • Faster readout for high throughput
  • Automatic assay initiation and plate identification
If you're looking for a highly sensitive instrument that fits your budget, EnVision® Xcite is the optimal choice. Designed to expand with your increasing throughput and applications needs, it delivers outstanding functionality, including:
  • Same sensitivity as EnVision® for lower throughput applications
  • Ability to upgrade as your needs change
  • User-changeable label-specific optical mirror modules and filters provide superior detection sensitivity and contribute to measurement speed. As your laboratory's application needs change or new applications come online, you can add more modules to extend EnVision's functionality.
  • A high energy excitation flash lamp reduces the number of repeated flashes needed, making the excitation cycle for detection as short as possible.
  • The fastest mode uses an innovative "on the fly"-detection - making EnVision exceptionally fast in measuring absorbance or fluorescence intensity on a 1536-well plate - less than 36 seconds including plate loading times!


Key System Features

  • Proprietary label-specific, bar-coded optical mirror modules and filters for assay customization and positive ID of measurement configuration.
  • Proprietary Direct Double Optics™ deliver a full lens system for maximum speed and sensitivity.
  • Supports all main non-radiometric technologies with kinetic and scanning measurements, high-power excitation and acceptance of a wide range of sample formats.
  • Easy networking and integration with lab automation systems.


Key Software Features

  • Intuitive user interface with real-time operator guidance tools, pre-set user-specific measurement protocols, mathematical curve fitting and auto-save functions for smooth operation.
  • Real-time kinetics display.
  • Flexible report formatting and automatic data export.
  • Optional 21 CFR Part 11 compliance.


Typical Performance

  • Fastest mode uses an innovative "on the fly"-detection – making EnVision exceptionally fast in measuring absorbance or fluorescence intensity on a 1536-well plate – less than 36 seconds including plate loading times
  • The Standard AlphaScreen upgrade allows a typical 384-well AlphaScreen plate to be measured in approximately 5 minutes 40 seconds
  • The AlphaScreen HTS upgrade allows a typical 384-well AlphaScreen plate to be measured in approximately 2 minutes and includes the Enhanced Luminescence feature

Options & Accessories

Options & Accessories

  • 20-plate or 50-plate Stackers
  • Temperature control, which includes:
    • Chamber temperature from +2°C above ambient to +42°C
    • Heats from minimum to +37°C in less than 15 minutes
    • Temperature Uniformity < 1°C at 37°C set point
    • Temperature Accuracy ±.0.75°C at 37°C set point
    • Advanced software control of upper/lower heating elements to prevent condensation
  • Enhanced security for 21 CFR Part 11 compliance
  • Application specific mirror modules and filters
  • Enhanced Luminescence option
  • Standard AlphaScreen and HTS AlphaScreen option, which include a lasers and a plate cooler
  • Plate barcode reader

Upgrade Options:

Monochromator: Turn your EnVision into the ultimate plate reader with the flexibility and wavelength scanning of a monochromator:

  • Absorbance Monochromator measures absorbance assays
  • Fluorescence Intensity Monochromator measures absorbance and fluorescence intensity with a high-performance quad monochromator package

AlphaScreen: With low backgrounds and high S/B ratios, AlphaScreen (Amplified Luminescent roximity Homogeneous Assay) technology is ideal for your most demanding screening assays. EnVision’s speed plus AlphaScreen’s sensitivity mean high throughput across a broad range of applications:

  • Standard Option for medium-throughput screening of up to 37,000 samples per day
  • HTS “Turbo” Option for high-throughput screening of almost 100,000 samples per day (includes Enhanced Luminescence Option)

The Standard AlphaScreen upgrade allows a typical 384-well AlphaScreen plate to be measured in approximately 5 minutes 40 seconds. The AlphaScreen HTS upgrade allows for the same plate to be measured in approximately 2 minutes and includes the Enhanced Luminescence feature as well.

TRF LASER: The TRF LASER greatly enhances time-resolved fluorescence performance by delivering a short, sharp excitation pulse, resulting in superior signal-to-noise ratios. And with our high-sensitivity DELFIA separation assays and fast LANCE homogeneous assays, the specificity of each lanthanide’s emission spectrum enables multiplexed TRF assays.

Enhanced Luminescence: When your assays require high sensitivity, this option gives you an additional luminescence detector.

Dispenser: With two pump units, a magnetic stirrer and a heater, the dispenser unit provides the ultimate functionality, including:

  • Precise delivery of reagents
  • Simultaneous dispensing and reading
  • Adjustable dispense speed
  • Real-time kinetics live display (shown at right)

Temperature Control: The EnVision® temperature control is ideal for cellular and enzyme kinetic assays, which require a defined temperature range. Chamber temperature can be regulated from +2°C above ambient to +45°C (+/- 1°C). The heating time from room temperature to +37°C is less than 10 minutes.

Plate Stacker Option: Available for 20 or 50 plates, plate stackers can be added to increase capacity and throughput. With easy integration into robotic systems and the ability to accept microplates up to 3456 wells, the stacker option greatly increases the throughput of kinetic assays: over 100,000 samples per day when 1536-well plates are used.

Additional Upgrade Options:

  • Enhanced security for 21 CFR Part 11 compliance
  • Light Source option for reading from the bottom of the
  • Plate barcode reader upgrade
  • Dual emission reader upgrade

Applications

Envision® – For All Major Assay Applications:

  • Cellular Assays: Below-reading, shaking, scanning and kinetics make EnVision the ideal tool for cellular assays. Temperature control and dispenser options also enable ion channel, flash luminescence, dual reporter gene assays and more.
  • GPCR Assays: Use fast-reading EnVision with our AlphaScreen®, TRF (LANCE™, DELFIA®) or FP technologies for GPCR assays.
  • Reporter Gene Assays: Scanning and kinetics capabilities and label-specific optical mirror modules and filters enable GFP assays and dual reporter gene assays using luciferase and beta lactamase.
  • Enzyme Assays: Perform sensitive kinetic measurements across a wide dynamic range, and high-speed measurements at short-repeat intervals.
  • Genotyping Assays: Fluorescent polarization mirror module and filters enable SNP genotyping.

Quantification Assays: A wide range of filters and optical mirror modules covering the UV/Vis spectrum enables direct measurement of DNA and protein for ELISAs, including AlphaLISA™, and immunoassays using different labels.