PerkinElmer
  • 研究领域
  • 治疗领域

癌症研究

通过不断探索癌症的复杂细节研发更有效的肿瘤治疗方案。我们丰富的癌症研究相关产品帮助您实现体外、体内、组织水平检测、成像以及数据分析。

  • 通过成像和分析组织切片样本进一步了解肿瘤微环境,探索新的疾病亚型和新型靶点。
  • 使用我们的小动物活体设备从分子、功能、解剖学角度出发研究动物模型对治疗的响应。
  • 通过我们的高内涵筛选系统和信息化解决方案获取更深入的肿瘤细胞表型信息。
  • 通过我们的多功能酶标仪进行多种实验和试剂快速灵敏的检测和评估关键的肿瘤标志物。
  • 我们提供自动化解决方案帮助您提升实验效率,进一步提高研发速度。

Explore Our Solutions

Genomics Solutions Cancer Research

Advances in genomic technologies has improved our understanding of the biology of cancer. Genomic approaches to cancer research can be use to study its mechanisms, improve biomarker discovery, and help drive targeted therapeutic discovery leading to new methods for diagnosing and treating the disease.

Our genomics solutions for cancer research cover multiple application areas including; DNA/RNA analysis, Nucleic Acid Isolation, CRISPR Analysis, and more. Our broad range of solutions are designed to improve the efficiency of your genomic cancer research from extraction to analysis.

  • Nucleic acid isolation
  • Whole genome sequencing
  • Exome sequencing
  • Targeted amplicon sequencing
  • Transcriptomics
  • Epigenomics
  • cfDNA research
  • PCR/qPCR
  • CRISPR edited genomes
  • Microbiome research/metagenomics

Learn more

Cell-Based Solutions Cancer Research

Cell-based assays are a proven and powerful tool for gaining a more complete understanding of cancer biology, providing more meaningful results in more physiologically relevant systems than classical biochemical assays - instrumental in streamlining cancer research and drug discovery.

Whether you are a basic researcher trying to better understand biological processes in cancer cells or investigating how drugs affect those processes, we have the tools you need to advance your cancer research and discovery.

Our cell-based cancer research solutions allow you to:

  • Gain deeper insights from phenotypic screening of live cancer cells, 3D cell models, and stem cells with our high content screening and informatics solutions
  • Monitor the health of cells with luminescence assays
  • Study the mechanisms of metal-based chemotherapy resistance in single cells using our innovative SC-ICP-MS system
  • Compliment traditional histochemistry techniques using IR spectroscopy to evaluate features of the tumor microenvironment

For research purposes only. Not for use in diagnostic procedures.

Applications & Techniques

High-Content Analysis

Cell imaging has revolutionized cancer biology by enabling cells to be seen more clearly and in more detail.

Take your cell imaging to the next level with high-content analysis:

  • Gain more information from cellular samples and complex 3D cell models
  • Create meaningful functional screening assays for the development of drugs which prevent tumor growth and metastasis
  • Answer more questions simultaneously with multi-parametric data sets that are more information-rich compared to non-imaging read-outs

Learn more

Cytotoxicity & Cell Proliferation Assays

Cytotoxicity and cell proliferation assays are widely used in cancer research and drug discovery providing valuable insights to the health of cells.

Learn more

Single Cell ICP-MS for Cancer Research

Study the mechanisms of metal-based chemotherapy at the cellular level in individual cancer cells using Single Cell ICP-MS.

  • Gain a better understanding of how cancer cells become resistant to metal-based chemotherapy
  • Study and quantify uptake of metal-based nanoparticles in single cells for targeted cancer therapy
  • Evaluate effects of potentially new metal-based therapies

Learn more

Tumor Microenvironment

Identify chemical and morphologic features of the tumor microenvironment using Fourier transform infrared (FT-IR) spectroscopic imaging.

  • Innovative stain-free approach to compliment traditional histochemistry techniques
  • Differentiate molecular differences between normal and diseased tissues
  • Research transition of normal cells into cancerous cells in the tumor microenvironment

Learn more

Learn more

Animal Imaging Solutions Cancer Research

Study cancer biology and assess therapeutic efficacy in vivo.

Small animal imaging is becoming an increasingly important tool for studying cancer research by providing investigators with unique capabilities to non-invasively detect and characterize cancer in vivo.

Whether you are monitoring tumor growth and progression, angiogenesis, metastases, performing drug efficacy and toxicology studies, or enhancing your understanding of cancer biology pathways, we have the tools to help with your next cancer discovery.

For research purposes only. Not for use in diagnostic procedures.

In vivo imaging workflow for cancer research

Learn more

Highlighted Applications

肿瘤免疫治疗与免疫学

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

Learn more

Single Cell ICP-MS for Cancer Research

Metal-based chemotherapies such as Cisplatin are the most widely used class of drugs for the treatment of various cancers. Initially patients respond well to these drugs but often later relapse as the cancer displays resistance to the therapy. Metal-based chemotherapy works by forming crosslinks in DNA creating blockages which results in the cancer cells inability to replicate. Cellular uptake of metal-based drugs is related to tumor burden and consequently low intracellular levels of the drug are proportional to a decrease in tumor response.

Until now there has been little or no data about the distribution of the drug within individual tumor cells as traditional techniques can only measure the average concentration across the whole cell population. It’s clear that cells in the same population do not behave in the same way and the need to understand individual cell behavior is a trend across life science research in general. As a result, there is a growing need to analyze cellular uptake and distribution of metal-based or nanoparticle delivery of chemotherapy at the single cell level to determine if treatment is effective.

The innovative NexION® Single Cell ICP-MS system includes nebulizer technology allowing introduction of cells, one by one, as well as new software to calculate metal concentrations per cell. These will enable you to gain a better understanding of the mechanisms of how resistance develops in metal-based chemotherapies. With the NexION system you can rapidly detect and quantify metal concentrations in individual cancer cells to yield critical data about metal distribution in the cell population. This information may not only help you better understand chemotherapy resistance but can also lead to potential new therapies for cancer including in combination with other treatments such as immunotherapy.

Learn more

Contact us to see how we can help you with your next cancer breakthrough