PerkinElmer

CNS

OF

CNS research seeks to advance treatment for central nervous system disorders through the discovery and quantitation of biomarkers, mechanisms, and drug targets. Our broad range of CNS products meets all the needs of in vitro, in situ, and in vivo central nervous system research.

We offer biomarker detection kits with AlphaLISA® and LANCE® TR-FRET technology, cellular and in vivo imaging systems, and tissue pathology solutions to assess mechanisms of CNS disease in biochemical, cellular, tissue, and animal models. We also provide target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes.

Applications for our CNS products include:

  • Measuring biomarkers of CNS disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types with our fast, pre-validated kits
  • Studying targeted binding using our radiolabeled ligands and steroids
  • Quantitating biomarkers in tissue samples with our industry-leading immunohistochemistry products
  • CNS research in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Performing phenotypic analysis with our high content screening solutions

Our CNS products are also well suited for CNS research in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Gain precise insight on disease biomarkers like phospho-tau, Ab42/Ab40, vimentin, and frataxin, as well as relevant receptors such as dopamine DA1R/DA2R.

  • 产品与服务

  • 资源,活动及更多信息

缩小结果
产品类型
  • Reagents (157)
  • Accessories (34)
  • Software and Informatics (7)
  • Consumables (2)
应用
  • Drug Discovery & Development (46)
  • In situ hybridization (ISH) (23)
  • Immunohistochemistry (IHC) (23)
  • Protein Analysis & Detection (16)
  • Molecular Biology (14)
  • cAMP (11)
检测点(200-50,000)
  • 500 (10)
  • 5000 (5)
  • 10000 (5)
检测目标
  • Aβ40 (3)
  • Frataxin (2)
  • Aβ1-40 (2)
  • BDNF (2)
  • TDP-43 (2)
  • GAD67 (2)
  • Aβ1-x (1)
  • Aβ42 (1)
  • EPO (1)
检测目标类
  • GPCR (80)
  • Protein (9)
  • Peptide (6)
  • Ion channel (3)
  • Cytokine (1)
检测验证
  • Binding (72)
  • Calcium Luminescence (32)
  • cAMP (20)
  • GTPγS (19)
  • Downstream Phosphorylation (5)
  • Calcium Fluorescence (16)
  • Inositol Phosphate (3)
自动化兼容
  • Yes (16)
缓冲
  • Tricine with stabilizer and dye (12)
  • Tricine (2)
浓度
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
检测方法
  • Fluorescence (25)
  • Radiometric (15)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
  • Alpha (6)
  • Chromogenic (6)
实验类型
  • In vitro (16)
荧光基团
  • Cy3 (8)
  • Fluorescein (6)
  • TMR (5)
  • Cy5 (4)
  • Coumarin (1)
格式
  • Slides (23)
  • Microplates (16)
宿主细胞
  • CHO-K1 (65)
  • HEK293 (13)
  • 1321N1 (4)
  • L Cells (1)
  • UC11 (1)
标签位置
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
核苷酸
  • UTP (4)
  • ATP (3)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • CTP (1)
  • GTP (1)
产品品牌名称
  • Membrane Target Systems (35)
  • Operetta (29)
  • ValiScreen (15)
  • AequoScreen (14)
  • TSA (12)
  • AequoZen (12)
  • TSA Plus (12)
  • LANCE Ultra (10)
  • Opera Phenix (7)
  • EasyTide (7)
  • cAMPZen (7)
  • AlphaLISA (6)
  • NEN Radiochemicals (6)
  • NEN (2)
  • Ancillary Products (2)
放射性核素
  • 33P (12)
  • 35S (2)
  • 3H (1)
放射性同位素
  • P-33 (12)
  • S-35 (2)
  • H-3 (1)
受体类型
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Opioid (11)
  • Galanin (10)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • Neurotensin (4)
  • GABA (4)
  • Nicotinic (4)
  • Tachykinin (1)
目标种
  • Human (16)
治疗领域
  • Central Nervous System (87)
  • Inflammation (51)
  • Cardiovascular (37)
  • Gastrointestinal (31)
  • Metabolic (30)
  • Pain (21)
  • Diabetes (10)
  • Angiogenesis (9)
  • CNS & Neurologic (1)
  • Obesity (1)
体积
  • 0-50 (1)
体积容量
  • 150 µL (2)

"CNS" 1-50200 产品与服务

每页
PerkinElmer

TSA Biotin Reagent Pack

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

UTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Uridine triphosphate, labeled on the alpha phosphate group with 33P.
PerkinElmer

Membrane Target Systems: Serotonin 5HT1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from cells stably-transfected with human serotonin 5HT1a receptor

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2B (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

ValiScreen Galanin Gal2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

BDNF (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human BDNF Detection Kit is designed for detection and quantitation of human BDNF in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
AlphaLISA immunoassay kits

Amyloid ß 1-x (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-x (Aß 1-x) Detection Kit is designed for detection and quantitation of human Aß 1-x in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Receptor-expressing cell lines

cAMPZen FroZen Cells, Galanin Gal1, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.

dTTP, [α-33P]- 3000Ci/mmol, 10mCi/ml, 1 mCi

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Deoxythymidine triphosphate, labeled on the alpha phosphate group with 33P.
LANCE Detection Kit

Aβ(1-40) (human) High Specificity LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Aβ(1-40) High Specificity Detection Kit is designed for detection and quantitation of human Aβ(1-40) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Mannose, D-[2-3H(N)]-, Specific Activity: 15-30Ci (555GBq-1.11TBq)/mmol, 5mCi (185MBq)

5 mCi quantities of D-[2-3H(N)]-Mannose are available for your research.
Receptor-expressing cell lines

ValiScreen Opioid Kappa (OP2) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Serotonin 5-HT1a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT1a receptor, in HEK-293 cells.
PerkinElmer

TSA Cyanine 3 Reagent Pack

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra Cy3 in the localized area of the probe or antibody.
PerkinElmer

TSA Fluorescein Reagent Pack

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
TSA Cyanine 3 System

TSA Cyanine 3 System, for 50-150 Slides

TSA® Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Receptor-expressing cell lines

AequoZen FroZen Cells, Galanin GAL2, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
PerkinElmer

Membrane Target Systems: Serotonin 5HT-6 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2C (non edited isoform), Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

Cannabinoid CB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT6, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
PerkinElmer

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.

GTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Guanosine triphosphate, labeled on the alpha phosphate group with 33P.
PerkinElmer

Membrane Target Systems: Dopamine D3 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

Frataxin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Receptor-expressing cell lines

Dopamine D2L AequoScreen Cell Line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA -Plus Fluorescein System

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
TSA Cyanine 3 System/Cyanine 5 System

TSA Plus Cyanine 3 and Cyanine 5 System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
AlphaLISA immunoassay kits

Amyloid β 1-42 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.

UTPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 35S.
TSA Biotin System

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Receptor-expressing cell lines

Opioid mu AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

AequoZen FroZen cells, Dopamine D2L, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
Receptor-expressing cell lines

cAMPZen Frozen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
PerkinElmer

Membrane Target Systems: Opioid Kappa (OP2) (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human opioid kappa (OP2) receptor, 400 units.
Amplification Diluent

TSA Cyanine 5 Tyramide Reagent Pack, Reagents for 50-150 Slides

TSA® Cyanine 5 (Cy5) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Receptor-expressing cell lines

Nicotinic HM74a Aequoscreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: Nociceptin NOP (ORL1) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Nociceptin NOP (ORL1) receptor, 400 units.
Receptor-expressing cell lines

AequoZen FroZen cells, Cannabinoid CB1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2C (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
Receptor-expressing cell lines

ValiScreen Nicotinic HM74a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Opioid Mu (OP3), Human Recombinant, CHO-K1 cAMPZen Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT5A Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.

"CNS" 1-50200 产品与服务

每页