PerkinElmer

对生物有机体的影响

人们逐渐开始担心微塑料对海洋生态系统和淡水生态系统的影响,尤其是食物链的影响。除浸出有害添加剂外,微塑料能够生成一层表面生物膜,而生物膜会聚集杀虫剂等有机污染物并吸引潜在有害的细菌。这种生物区被海洋生物摄入之后会对生物体本身、食物链和人体健康造成潜在影响。微塑料如何影响生物有机体的生殖、生长和繁殖,以及免疫应答的变化,以及如何导致感染性提高等问题都是至关重要的,因为这些问题都会影响食物链。针对身体的伤害,有证据表明渗透到组织或大脑的微小颗粒会导致行为变化。该研究需要细胞成像和分析技术、基因测序和蛋白质组学工具。

典型应用包括:

  • 细胞应激反应和炎症、氧化应激反应、细胞毒性、细胞活力和激素分析
  • 活性氧类(ROS)研究
  • 细胞侵袭、摄取和定位研究
  • 定位和分析嵌入组织和细胞内的微小颗粒
  • 组织中塑料微粒的识别、特征描述和大小计算
  • 成像技术,用于追踪活鱼和甲壳纲动物体内的感染和免疫应答
  • 生物膜细菌基因组的下一代测序技术
  • 纳米颗粒分析

仅供科学研究使用。不适用于临床诊断。

解决方案

NGS 建库试剂盒

NEXTflex® library preparation kits are designed to reduce bias and increase the sensitivity, flexibility, and speed of library prep for both Illumina® and Ion Torrent sequencing platforms. An extensive selection of NEXTflex single index and dual index barcoded adapters is available to meet your specific multiplexing needs. Automation protocols for the PerkinElmer® Sciclone® NGS Workstation are available for many of the NEXTflex library prep kits for labs requiring higher sample throughput, reduced hands-on time, greater reproducibility, or improved process control.

For research use only. Not for use with diagnostic procedures.

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Opera Phenix高内涵筛选系统

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.

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EnSight 多模式读板仪

The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

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AlphaLISA SureFire Ultrap-JNK1/2/3 (Thr183/Tyr185) HV 试剂盒,100个检测点

The AlphaLISA® SureFire® Ultra™ p-JNK1/2/3 (Thr183/Tyr185) HV (high volume) assay is a sandwich immunoassay for quantitative detection of phospho-JNK1/2/3 (phosphorylated on Thr183/Tyr185) in cellular lysates using Alpha no-wash technology.

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Operetta CLS 高内涵分析系统

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.

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Sciclone® G3 NGS 和 NGSx 工作站

The Sciclone® G3 NGS and NGSx workstations area complete benchtop solution for the automated construction of up to or greater than 96 libraries per day.

Next generation sequencing (NGS) technologies are enabling science at unprecedented rates. As the cost of sequencing declines, throughput continues to increase and the number of applications for which sequencing data can be used is expanding. The Sciclone® G3 NGS and NGSx liquid handling workstation was designed for high throughput, walkaway NGS sample preparation. The deck design and intuitive interface virtually eliminate cross contamination and user error. These liquid handlers simplify the construction of up to or greater than 96 libraries per day.

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Zephyr® G3 NGS工作站

The Zephyr® G3 NGS workstation is a benchtop liquid handler designed to automate the construction of 48 to 96 next generation sequencing (NGS) libraries per day. The simplified user-interface and integrated hardware maximize laboratory productivity while reducing variability resulting from manual pipetting.

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JANUS® G3 NGS Express工作站

The JANUS® G3 NGS Express workstation is a benchtop platform designed to simplify and reduce errors in low-to-moderate throughput NGS library construction. It uses an intuitive interface to guide users through protocol selection and deck setup, as well as, displays in-run status and details. An optional enclosure not only helps to minimize sample contamination, but the easy to read status lights provide visual feedback for true walkaway sample preparation.

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对生物有机体的影响——见解与学习

监测淡水藻类对金纳米颗粒和金离子的摄入行为

这项研究证明如何通过单细胞 ICP-MS(SC-ICP-MS)……

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通过细胞核表型分析来区分细胞类型

这个实验表明了单核染色如何实现表型分析...

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用高内涵筛选系统进行FRET测定

在这个实验中,我们建立了一种快速稳定的基于FRET的高内涵检测...

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