PerkinElmer

碘化合物

OF

We provide 125I- and 131I-labeled compounds, including radioligands specific for receptor/ligand characterization for drug discovery/development and receptor distribution. Because 125I and 131I are gamma emitters, they can be counted directly without requiring scintillant. Additionally, because 125I emits Auger electrons, counting in a liquid scintillation counter is also possible.

  • 产品与服务

  • 资源,活动及更多信息

缩小结果
应用
  • Drug Discovery & Development (73)
浓度
  • 345 µCi/mL (3)
  • 353 µCi/mL (3)
  • <1.0 µCi/mL (3)
  • 41.4 µCi/mL (2)
  • 79.2 µCi/mL (2)
  • 182 µCi/mL (2)
  • 87.2 µCi/mL (1)
  • 93.2 µCi/mL (1)
  • 3.06 MBq/mL (1)
  • 33.7 µCi (1)
  • 152 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 1.12 mCi/mL (1)
  • 1.14 mCi/mL (1)
  • 2.93 MBq/mL (1)
  • 50 µCi/mL (1)
  • 172.5 µCi/mL (1)
  • 236 µCi (1)
  • 83.8 µCi/mL (1)
  • 173.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 3.22 MBq/mL (1)
  • 42.5 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 171 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 1.0 - 10 mCi/mL (1)
  • 45.7 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • <100 µCi/mL (1)
检测方法
  • Radiometric (74)
标签位置
  • Nominally Labeled (69)
  • Specifically Labeled (5)
产品品牌名称
  • NEN Radiolabeled Ligands (72)
放射性核素
  • 125I (74)
受体类型
  • Chemokine (5)
  • Angiotensin (4)
  • Tachykinin (3)
  • Thyroid Hormone (3)
  • Glucagon (3)
  • Insulin (3)
  • Neuropeptide Y (3)
  • Bombesin (2)
  • Adrenoceptors (2)
  • Nicotinic (2)
  • Somatostatin (2)
  • Calcitonin (2)
  • Calcium (2)
  • Vasopressin (2)
  • Vasoactive Intestinal Peptide (2)
  • Cholecystokinin (1)
  • Transforming Growth Factor (1)
  • Apelin (1)
  • Melatonin (1)
  • Urotensin (1)
  • Endothelin (1)
  • Oxytocin (1)
  • SK channels (1)
  • Adenosine (1)
  • Dopamine (1)
  • Growth Hormone (1)
  • Melanocortin (1)
  • Orexin (1)
  • Interleukin (1)
  • Motilin (1)
  • Insulin-like Growth Factor (1)
  • Ghrelin (1)
  • Gonadotropin-releasing Hormone (1)
  • Melanin-Concentrating Hormone (1)
  • Neurotensin (1)
  • Corticotropin-Releasing Factor (1)
  • Epidermal Growth Factor (1)
治疗领域
  • CNS & Neurologic (35)
  • Inflammation (24)
  • Metabolic Disorders (21)
  • Cardiovascular (20)
  • Gastrointestinal (11)
  • Cancer (8)
  • Pain (8)
  • Angiogenesis (7)
  • Diabetes (7)
  • Obesity (5)
体积
  • 0-50 (8)
  • 51-100 (1)
  • 201-250 (1)

"碘化合物" 1-5074 产品与服务

Alpha Bungarotoxin

Recombinant Protein A, [125I]-, 100µCi (3.7MBq)

Recombinant Protein A, labeled with 125I. I-125 labeled Protein A can be used as a general tracer to capture antibodies in radioimmunoassays (RIAs).
Alpha Bungarotoxin

Recombinant Protein A, [125I]

Recombinant Protein A, labeled with 125I. I-125 labeled Protein A can be used as a general tracer to capture antibodies in radioimmunoassays (RIAs).
Alpha Bungarotoxin

Substance P, [125I] Tyr8]

Substance P, labeled with 125I on tyrosine residue 8. Substance-P acts as an antagonist at neurokinin-1 receptors (NK1Rs).
Alpha Bungarotoxin

MCP-1,[125I]- labeled, Bolton-Hunter Labeled

Monocyte chemoattractant protein 1 (MCP-1; CCL2), labeled with 125I. MCP-1 is a cytokine released by tumor cells that binds chemokine receptor 2 (CCR2).
Alpha Bungarotoxin

Iodo-(±)-Cyanopindolol, [125I]

Iodo-(±)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
Alpha Bungarotoxin

Bombesin, [125I]Tyr4

Bombesin, labeled with 125I on the tyrosine 4 residue. Bombesin is an endogenous agonist for bombesin receptors (BB1, BB2, BB3), and is also a tumor marker for certain cancers.
Alpha Bungarotoxin

Neurokinin A, ([125I]-Substance K

Neurokinin A (Substance K), labeled with 125I. Neurokinin A is a member of the tachykinin family of neuropeptide neurotransmitters, and is an endogenous agonist for NK-2 receptors. NK-2 receptors are potential drug targets for depression.
Alpha Bungarotoxin

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled

Interferon gamma-induced protein 10 (IP-10; CXCL10), labeled with 125I. IP-10 binds the chemokine CXCR3 receptor, and is secreted in response to IFN-γ.
Alpha Bungarotoxin

Fractalkine (human, recombinant), 125I

Fractalkine (CX3CL1), labeled with 125I. Fractalkine binds to chemokine receptor CX3CR1, and is involved in the adhesion and migration of leukocytes.
Alpha Bungarotoxin

Apamin [125I]His18-NH2

Apamin, labeled with 125I on histidine residue 18. Apamin is a neurotoxin that acts as an antagonist at calcium-activated potassium channels (SK channels).
Alpha Bungarotoxin

Guanosine 3`,5`-cyclic Phosphoric Acid, 2`-O-succinyl Iodotyrosine Methyl Ester, [125I]

cGMP, labeled with 125I on the tyrosine methyl ester group. I-125 labeled cGMP can be used as a tracer for radioimmunoassays to detect levels of endogenous cGMP in a sample.
Alpha Bungarotoxin

2`-Deoxycytidine-5`-triphosphate, 5-[125I] iodo-, Tetraammonium Salt

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
Alpha Bungarotoxin

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled

Cholecystokinin Octapeptide (CCK-8), labeled with 125I. Cholecystokinin is a neuropeptide that exists in several forms, identified by the number of amino acids in the peptide sequence. CCK8 contains 8 amino acids. The sulphated version of cholecystokinin can bind both Cholecystokinin A and Cholecystokinin B receptors. These receptors are involved in anxiety, feeding, and locomotion and are potential drug targets for depression and satiety.
Alpha Bungarotoxin

GLP-1 (7-36), [125I]

Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.
Alpha Bungarotoxin

Iodo-(-)-Cyanopindolol, [125I]

Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
Alpha Bungarotoxin

Ω-Conotoxin MVIIC, [125I]

Ω-Conotoxin MVIIC (ω-Conotoxin MVIIC), labeled with 125I. Ω-Conotoxin MVIIC is a neurotoxin that blocks calcium channels.
Alpha Bungarotoxin

Insulin-like Growth Factor-I (human, recombinant), 125I

Insulin-like growth factor 1 (IGF-1), labeled with 125I. IGF-1 acts as an agonist at the IGF-1 receptor, a receptor tyrosine kinase, that plays a role in growth, cancer, and aging. IGF-1 also binds the insulin receptor (IR), another receptor tyrosine kinase involved in glucose homeostasis, diabetes, and cancer.
Alpha Bungarotoxin

IL-6 (human, recombinant), [125I]

Interleukin 6 (IL-6), labeled with 125I. IL-6 is a cytokine that regulates cell growth, cell differentiation, and immune response, and binds to the interleukin 6 receptor (IL6R; CD126).
Alpha Bungarotoxin

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
Alpha Bungarotoxin

N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
Alpha Bungarotoxin

RTI-55, [125I]

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.
Alpha Bungarotoxin

α-MSH, Nle4, D-Phe7, [125I]

α-Melanocyte-stimulating hormone (α-MSH), labeled with 125I. α-MSH is an endogenous hormone that acts as a non-selective full agonist of melanocortin receptors MC1, MC3, MC4, and MC5.
Alpha Bungarotoxin

CGP 42112A, [125I]

CGP 42112A, labeled with 125I. CGP 42112A acts as an agonist at angiotensin AT2 receptors.
Alpha Bungarotoxin

S365057, [Tyr 125I]

NEX396 S36057 is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Alpha Bungarotoxin

α-Bungarotoxin, [125I]-Tyr54

α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.
Alpha Bungarotoxin

Iodo-Melatonin, 2-[125I]

Melatonin, labeled with 125I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.
Alpha Bungarotoxin

Insulin (human, recombinant), [125I]

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
Alpha Bungarotoxin

Gastric Inhibitory Polypeptide (human), [125I]

Gastric inhibitor polypeptide (GIP), labeled with 125I. GIP is a hormone that binds receptors found on beta cells in the pancreas.
Alpha Bungarotoxin

Orexin A, [125I]

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.
Alpha Bungarotoxin

Glucagon, Receptor Grade, [125I]

Glucagon, labeled with 125I. This product is receptor grade, and was developed for use in receptor binding assays. Glucagon binds and activates glucagon receptor, a GPCR that is a potential drug target for diabetes, hyperplasia, and pancreatic disorders.
Alpha Bungarotoxin

Endothelin-1 (human, porcine), [125I]Tyr13

Endothelin-1 (ET-1), labeled with 125I on the tyrosine 13 residue. Endoethlin-1 is a vasoconstrictor that acts as an endogenous agonist at endothelin receptors. Endothelin receptors are a class of GPCRs that are potential drug targets for hypertension and cancer.
Alpha Bungarotoxin

Somatostatin, [125I]Tyr11

Somatostatin, labeled with 125I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.
Alpha Bungarotoxin

Thyroxine, ([125I]-T4), 5700 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Alpha Bungarotoxin

Apelin 13 [125I]

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.
Alpha Bungarotoxin

TGF-β1 (human, recombinant), [125I]

Transforming growth factor beta 1 (TGF-β1), labeled with 125I. TGF-β1 is a cytokine that is involved in cell growth, cell differentiation, and apoptosis.
Alpha Bungarotoxin

Triiodothyronine, ([125I]-T3), Specific Activity: 3300 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Somatostatin-14 (human, recombinant), [125I], Receptor Grade

NEX446 Tyr11 Somatostatin-14 is radioiodinated with no-carrier-added 125I using amodified lactoperoxidase procedure and is purified by reversed phase HPLC. This method predominantly labels tyrosine residues.
Alpha Bungarotoxin

MIP-1α (human, recombinant), [125I]

Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with 125I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.
Alpha Bungarotoxin

Pancreatic Polypeptide (human), [125I]

Human pancreatic polypeptide (PP), labeled with 125I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.
Alpha Bungarotoxin

Epibatidine, ([125I]-IPH), [125I]

Epibatidine, labeled with 125I. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin 5-HT3 receptors.
Alpha Bungarotoxin

Thyroxine, ([125I]-T4), Specific Activity: 1080-1320 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Alpha Bungarotoxin

2'-deoxycytidine-5'-triphosphate, 5-[125I]Iodo-

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
Alpha Bungarotoxin

Ornithine Vasotocin Analog, [125I]-OVTA)

Ornithine Vasotocin Analog (OVTA), labeled with 125I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.
Alpha Bungarotoxin

Angiotensin I (human), [125I]Tyr4

Angiotensin I, labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin I is the precursor to Angiotensin II, which a peptide hormone that causes vasoconstriction and increased blood pressure, and is a potential drug target for blood pressure regulation.
Alpha Bungarotoxin

Ω-Conotoxin GVIA, [125I] Tyr22

Ω-Conotoxin GVIA (ω-Conotoxin GVIA), labeled with 125I on tyrosine residue 22. Omega conotoxin CVIA is a calcium channel blocker.
Alpha Bungarotoxin

Motilin, [125I]

Motilin, labeled with 125I. Motilin is a peptide hormone that binds motilin receptors, and stimulates contraction of gut smooth muscle.
Alpha Bungarotoxin

Vasopressin, [125I]Tyr2, Arg8

Vasopressin, labeled with 125I on tyrosine residue 2. Vasopressin binds and activates vasopressin receptors, a group of GPCRs that are potential drug targets for hyponatremia, congestive heart failure, and cirrhosis.
Alpha Bungarotoxin

Thyroxine, ([125I]-T4), Specific Activity: 135-165 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Alpha Bungarotoxin

Triiodothyronine, ([125I]-T3), Specific Activity: 1080-1320 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Alpha Bungarotoxin

Sauvagine, [125I]-Tyr0]

Sauvagine, labeled with 125I on the tyrosine 0 residue. Sauvagine is a neuropeptide that acts as an agonist at corticotropin-releasing factor receptors (CRF receptors) 1 and 2.

"碘化合物" 1-5074 产品与服务