PerkinElmer

放射化学试剂

OF

Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. The technique achieves sub-femtogram sensitivity levels, and quantitates the binding and activity of radiolabeled compounds with high specificity and sensitivity. As the leading supplier of research radiochemicals, we offer a broad portfolio of products for any radiochemistry need.

Our radiochemical analysis products include:

  • Radionuclides such as 124I, 14C, 89Zr, 90Y, 125I, 131I, 22Na, 32P, 33P, 35S, 3H, 45Ca, 51Cr, 54Mn, 55Fe, 59Fe, 85Sr, 86Rb
  • EasyTag protein labeling mixes
  • EasyTide radiolabeled nucleotides
  • NEN radiolabeled compounds
  • SPA Enzymatic assays and imaging beads

Our radiolabeled compounds are useful in a wide range of applications:

  • Research in cancer, CNS and neurologic disease, cardiovascular and metabolic disease, inflammation, and other disorders
  • Kinetic and mechanistic studies
  • Scintillation assays
  • Radiometric cAMP assays
  • Detection of binding to over 80 different receptor types

Our radiometric reagents are not reliant on the use of antibodies for detection and read-out – just one of the reasons they are so widely used.

For research and investigational use only.

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应用
  • Drug Discovery & Development (339)
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  • cAMP (2)
检测目标
  • cGMP (1)
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自动化兼容
  • Yes (27)
  • No (20)
缓冲
  • Tricine with stabilizer and dye (55)
  • Tricine (51)
  • Aqueous (39)
  • Ethanol : water (14)
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  • Ethanol 70% (3)
  • HCl (3)
  • NaOH pH 8-11 (2)
  • Sulfuric acid:ethanol (2)
  • NaOH pH 12-14 (2)
  • Ethanol 10% (2)
  • EDTA (1)
  • Ethanol 2% (2)
  • Aqueous PT6-271 Stabilizer (2)
  • Ethanol:water (2)
涂层处理
  • WGA (17)
  • HIS (2)
  • Nickel chelate (HIS-tag) (2)
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浓度
  • 1.0 - 10 mCi/mL (86)
  • 1 mCi/mL (73)
  • 10 mCi/mL (55)
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  • <1.0 mCi/mL (34)
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  • 0.55 mCi/mL (2)
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  • 236 µCi (1)
  • 83.8 µCi/mL (1)
  • 0.005 mCi/mL (1)
  • 173.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
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  • 496.19 mCi/mL (1)
  • 321.15 mCi/mL (1)
  • 18.75 mCi/mL (1)
  • 3.22 MBq/mL (1)
  • 103.23 mCi/mL (1)
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  • 6.05 MBq/mL (1)
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  • 10.2 mCi/mL (1)
  • 348.31 mCi/mL (1)
  • 87.4 µCi/mL (1)
  • 171 µCi/mL (1)
  • 93.2 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 1.12 mCi/mL (1)
  • 60.36 mCi/mL (1)
  • 347.65 mCi/mL (1)
  • 10.25 mCi/mL (1)
  • 16.26 mCi/mL (1)
  • 22.08 mCi/mL (1)
  • 1.14 mCi/mL (1)
  • 62.57 mCi/mL (1)
  • 2.93 MBq/mL (1)
  • 18.9 mCi/mL (1)
检测方法
  • Radiometric (708)
格式
  • Tubes (14)
  • Microplates (11)
标签位置
  • Specifically Labeled (332)
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  • alpha (81)
  • gamma (24)
  • Generally Labeled (14)
  • Uniformly Labeled (29)
核苷酸
  • UTP (24)
  • dATP (15)
  • ATP (29)
  • dTTP (16)
  • dCTP (14)
  • CTP (13)
  • pCp (2)
  • dGTP (4)
  • GTP (12)
  • NAD (2)
产品品牌名称
  • NEN Radiochemicals (513)
  • NEN Radiolabeled Ligands (72)
  • EasyTide (49)
  • SPA Imaging Beads (18)
  • SPA Scintillation Beads (26)
  • NEN (10)
  • EasyTag (1)
  • CytoStar-T (4)
  • SPA Enzymatic Assays (3)
放射性核素
  • 3H (299)
  • 32P (91)
  • 14C (116)
  • 125I (81)
  • 35S (28)
  • 33P (15)
  • 51Cr (4)
  • 59Fe (2)
  • 45Ca (1)
  • 22Na (1)
  • 124I (1)
  • 86Rb (1)
  • 14C (1)
  • 54Mn (1)
  • 89Zr (1)
  • 85Sr (1)
  • 131I (8)
  • 3H (1)
  • 55Fe (1)
  • 90Y (1)
放射性同位素
  • H-3 (304)
  • C-14 (120)
  • P-32 (92)
  • I-125 (81)
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  • P-33 (15)
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受体类型
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  • TRP Channels (3)
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  • Neurotensin (2)
  • Somatostatin (2)
  • Vasoactive Intestinal Peptide (2)
  • Dopamine Transporter (2)
  • hERG (2)
  • Oxytocin (2)
  • Retinoic Acid Receptors (2)
  • Calcitonin (2)
  • ASBT (2)
  • Organic zwitterions/cation transporters (OCTN) (2)
  • Bombesin (2)
  • Bradykinin (1)
  • Inositol Triphosphate (1)
  • SK channels (1)
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治疗领域
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  • Metabolic Disorders (86)
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  • Pain (36)
  • Cancer (31)
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  • Obesity (6)
  • Musculoskeletal (1)
体积
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  • 201-250 (125)
  • 51-100 (3)

"放射化学试剂" 1-50729 产品与服务

每页

Methyl-D-glucose, 3-O-[Methyl-14C]

50 µCi quantities of 3-0-[Methyl-14C]-Methyl-D-glucose are available for your research.

Glibenclamide, Glyburide, [Cyclohexyl-2,3-3H(N)]-, 250µCi (9.25MBq)

Glibenclamide (glyburide) tritiated at the cyclohexyl-2,3 position. Glibenclamide is an antidiabetic drug that binds and inhibits the ATP-sensitive potassium channel.

Fractalkine (human, recombinant), 125I

Fractalkine (CX3CL1), labeled with 125I. Fractalkine binds to chemokine receptor CX3CR1, and is involved in the adhesion and migration of leukocytes.

UTP, [α-32P]- 3000Ci/mmol 10mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 32P.

Serine, L-[3H(G)]

5 mCi quantities of L-[3H(G)]-Serine are available for your research

Progesterone, [1,2,6,7-3H(N)]-, 250µCi (9.25MBq)

250 µCi quantities of [1, 2, 6, 7-3H(N)]-Progesterone are available for your research.

Digoxin, [3H(G)]-, 250µCi (9.25MBq)

250 µCi quantities of [3H(G)]-Digoxin are available for your research.

Adenosine 3`, 5`-Cyclic Phosphate, Ammonium Salt, [2,8-3H]-, 250µCi (9.25MBq)

250 µCi quantities of Adenosine 3', 5'-Cyclic Phosphate, Ammonium Salt, [2,8-3H] are available for your research.

IL-6 (human, recombinant), [125I]

Interleukin 6 (IL-6), labeled with 125I. IL-6 is a cytokine that regulates cell growth, cell differentiation, and immune response, and binds to the interleukin 6 receptor (IL6R; CD126).

Mazindol, [4`-3H]-, 250µCi (9.25MBq)

Mazindol, tritiated at the 4' position. Mazindol has been shown to block dopamine (DAT), serotonin (SERT), and norepinephrine (NET) transporters.

Tryptophan, L-[side chain-3-14C]-,>97%

10 µCi quantities of L-[side chain-3-14C]-Tryptophan are available for your research.

dCTP, [α-32P]- 6000Ci/mmol 20mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 32P.

GTP, [α-32P]- 3000Ci/mmol 10mCi/ml

Guanosine triphosphate, labeled on the alpha phosphate group with 32P.

Deltorphin II (2-D-Ala), [Tyrosyl-3,5-3H]

Deltorphin II, tritiated at the tyrosyl-3,5 position. Deltorphin II is a selective δ opioid receptor (DOPR) agonist.

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

As of August 17, 2018, we will be discontinuing all P33 nucleotides and P33 nuclides. The last day for shipping any of these products will be August 16, 2018. Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.

Thymidine, [Methyl-3H]-, Specific Activity: 70-90Ci (2.59-3.33TBq)/mMole,>97%, 250µCi (9.25MBq)

250 µCi quantities of tritiated thymidine are available for your research.
PerkinElmer

HIS-Tag Beads PS 500 MG

SPA beads for capturing His-tagged proteins and peptides.

MK-801, (+)-[3-3H]-

(+)-MK-801 radioligand tritriated at the 3 position. MK-801 acts as a non-competitive antagonist at the glutamate receptor, N-Methyl-D-aspartate (NMDA).

Uridine Diphosphate Glucuronic Acid, [Glucuronyl-14C(U)]-, 50µCi (1.85MBq)

50 µCi quantities of [Glucuronyl-14C(U)]-Uridine Diphosphate Glucuronic Acid are available for your research.

CGRP (human), [125I]

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.

Dihydroxyvitamin D3, 1 α, 25-[26,27-3H]-, 5µCi (185kBq)

Dihydroxyvitamin D3, 1 α, 25-[26,27-3H]- will have fresh lot dates on the second Monday in April and October.

Thymidine, [2-14C]-,>97%, 50µCi (1.85MBq)

50 µCi quantities of [2-14C]-Thymidine are available for your research.

N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

Chromium-51 Radionuclide, Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

Deoxy-D-glucose, 2-[14C(U)]

50 µCi quantities of 2-[14C(U)]-Deoxy-D-Glucose are available for your research.

Hydrocortisone (Cortisol, [1,2,6,7-3H(N)]-), [1,2,6,7-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of [1, 2, 6, 7-3H(N)]-Hydrocortisone (Cortisol) are available for your research. 

ATP, [γ-32P]- 3000Ci/mmol 10mCi/ml EasyTide

Adenosine triphosphate, labeled on the gamma phosphate group with 32P.

Sodium Cyanide, [14C], 1mCi (37MBq)

1 mCi quantities of [14C]-Sodium Cyanide are available for your research.

GR 65630, [N-Methyl-3H]

GR 65630, tritiated on the N-methyl group. GR 65630 acts as a selective antagonist at the 5-HT3 receptor.
PerkinElmer

WGA PVT SPECIAL 25 X 500 MG

Wheat germ agglutinin (WGA), PEI-coated SPA beads, for proximity-based radiometric scintillation assays. The treatment of PVT-WGA SPA beads with positively charged polyethyleneimine (PEI) blocks potential non-specific binding sites on the SPA bead surface.

dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide Lead

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 32P.

Inositol-1,4,5-Triphosphate, D-[Inositol-1-3H(N)]

5 µCi quantities of D-[Inositol-1-3H(N)]-Inositol-1,4,5-TrisPhosphate are available for your research.

dATPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 35S.

Imipramine Hydrochloride, [Benzene ring-3H(N)]-, 250µCi (9.25MBq)

Imipramine hydrochloride, tritiated on the benzene ring. Imipramine is believed to act as an antagonist at certain serotonin, histamine, and cholinergic receptors.

Substance-P (9-Sar, 11-Met(O2)), [2-Prolyl-3,4-3H]-, 50µCi (1.85MBq)

Substance-P, tritiated on the 2-prolyl group. Substance-P acts as an antagonist at neurokinin-1 receptors (NK1Rs).

Iron-59 Radionuclide, Ferric Chloride in 0.5M HCl

Iron-59 Radionuclide Ferric chloride in 0.5M HCl Shipped ambient. Iron chloride in 0.5M HCI>5Ci(185GBq)/g

Neurotensin, [125I]Tyr3]

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.

Fibrinogen, 125I human , 110 µCi

Human fibrinogen, labeled with 125I. Fibrinogen is a glycoprotein that promotes blood clotting by activating blood platelets through binding to their GpIIb/IIIa surface membrane fibrinogen receptor.

dATP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 32P.

Triiodothyronine, ([125I]-T3), Specific Activity: 3300 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

PcP, [5`-32P]- 3000Ci/mmol 10mCi/ml Lead, 250 µCi

Cytidine 3', 5' bis(phosphate) (pCp) is labeled on the 5' phosphate group with 32P.

Thymidine, [Methyl-3H]

1 mCi quantities of tritiated thymidine are available for your research.
PerkinElmer

Streptavidin YOX Imaging Beads 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I]

Vasoactive intestinal polypeptide (VIP), labeled with 125I. VIP binds vasoactive intestinal peptide receptors VPAC1 and VPAC2, a group of GPCRs that are potential drug targets for nervous and endocrine disorders and several types of cancer.

Inositol, Myo, -[2-3H(N)]-, Specific Activity: 10-25Ci (370-925GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of Myo-[2-3H(N)]-Inositol are available for your research.

Thymidine, [2-14C]-,>97%, 250µCi (9.25MBq)

250 µCi quantities of [2-14C]-Thymidine are available for your research.

"放射化学试剂" 1-50729 产品与服务

每页