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Apelin 13 [125I], 50 µCi

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.

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部件号
产品尺寸
NEX393010UC
10 µCi
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NEX393025UC
25 µCi
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NEX393050UC
50 µCi
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详情 信息

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX393:

  1. Ma, Y. et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure 25, 858–866.e4 (2017).

规格

浓度 172.5 µCi/mL
检测方法 Radiometric
新鲜的很多天 Fresh upon request
标签位置 Nominally Labeled
产品品牌名称 NEN Radiolabeled Ligands
放射性同位素 I-125
受体类型 Apelin
运输条件 干冰
特殊订购信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
治疗领域 CNS & Neurologic, Cardiovascular, Gastrointestinal
产品尺寸 50 µCi