Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
BombesinRSense™ 680 targeted near infrared (NIR) fluorescent imaging agent is specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas.
BombesinRSense 680 comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.
免责声明: For laboratory use only. This product is intended for animal research only and not for use in humans.
|产品尺寸||1 Vial (10 doses)|
|数据单表||BombesinRSense 680 (Data Sheet)||PDF 136 KB|
|技术说明||BombesinRSense 680 (Protocol)||PDF 257 KB|
|应用文献||Development of a Near Infrared Fluorescent Labeled Agent for Assessing Bombesin Receptor Expression||PDF 1 MB|
|海报||Optical imaging of bombesin and transferrin receptor expression is comparable to 18F-FDG in assessin||PDF 2 MB|