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Chromium-51 Radionuclide, 1mCi (37MBq), Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

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部件号
产品尺寸
NEZ030S001MC
1 mCi
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NEZ030S002MC
2 mCi
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NEZ030S005MC
5 mCi
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NEZ030S010MC
10 mCi
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详情 信息

Chromium-51 is the most commonly used readioactive marker for the labeling of target cells in cytotoxicity assays. The common name for such assays Chromium Release also describes the fundamental method behind the assay procedure. Methods for the precise and accurate quantification of cytotoxicity are of fundamental importance in immunology particularly for the study of tumor and virus cytolysis.
Cytotoxicity assays can be used in order to study either the defense mechanism in a specific patient or to study target cells, depending on whether the effector (or killer) cells are the unknowns. It can also be used for the study of certain drugs on the immune system.
Chromium fulfills the requirement of a good label. It is generally non-toxic (as Na2CrO4), it is easily taken up by the cells, it is spontaneously released only in relatively small amounts, its detection is easy and sensitive and it does not change the morphology and characteristics of the target cell.

规格

浓度 1 mCi/mL
检测方法 Radiometric
新鲜的很多天 Every other Friday
半衰期 27.71 days
标签位置 Specifically Labeled
放射性同位素 Cr-51
放射性核素 51Cr
运输条件 环境
特殊订购信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
产品尺寸 1 mCi
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产品手册

Radiometric Reagents Guide 2010-2011

For over 50 years PerkinElmer has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed today.

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指南

Carbon-14 Handling Precautions

This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.

PDF 102 KB
Chromium-51 Handling Precautions

This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.

PDF 107 KB