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IntegriSense 645 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 







Integrins are transmembrane cell surface receptors which mediate signal transduction, cell-to-cell interaction and cell-to extracellular matrix adhesion, key processes involved in angiogenesis, tumorigenesis and metastasis. Integrins have thus been hailed as clinically-relevant biomarkers of pathological conditions such as inflammation and tumor progression. The integrin avb3 is significantly upregulated in tumor cells and activated endothelial cells during neoangiogenesis. 

IntegriSense™ 645 fluorescent imaging agent is used for in vivo detection of avb3 using a low molecular weight peptidomimetic antagonist coupled to a red fluorochrome. IntegriSense 645, an integrin-targeted molecular imaging agent allows the non-invasive imaging of disease status and progression. Pairing of an integrin antagonist treatment with IntegriSense 645 provides a mechanistic biomarker approach for assessing target coverage. 

免责声明:  For laboratory use only. This product is intended for animal research only and not for use in humans.


荧光剂类型 Targeted
光学成像分类 Fluorescence Imaging
产品品牌名称 IntegriSense
包装量 1.0 Units
运输条件 蓝冰
治疗领域 Angiogenesis, Atherosclerosis, Oncology/Cancer
产品尺寸 1 Vial (10 doses)
波长 645 nm


所有 (6)
资源类型 文件名 文件格式
产品手册 FMT Fluorescence Tomography in vivo Imaging Systems PDF  1 MB
产品手册 In Vivo Imaging Agents Brochure PDF  2 MB
应用文献 In Vivo Imaging of Atherosclerosis Disease Using FMT PDF  1 MB
技术说明 IntegriSense™ 645 (Data Sheet) PDF  105 KB
Citations Library View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents 链接
网络研讨会 View our complete list of in vivo webinars available on demand 链接