Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6).
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Lysergic Acid Diethylamide (LSD) is a psychedelic drug that acts as an agonist at dopamine D2 receptors and serotonin receptors 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET638:
浓度 | 1.0 - 10 mCi/mL |
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检测方法 | Radiometric |
标签位置 | Specifically Labeled |
分子量 | 323.4 |
产品品牌名称 | NEN Radiochemicals |
放射性同位素 | H-3 |
放射性核素 | 3H |
受体类型 | 5-Hydroxytryptamine |
运输条件 | 干冰 |
特殊订购信息 | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
治疗领域 | CNS & Neurologic, Cardiovascular, Inflammation, Metabolic Disorders, Gastrointestinal |
产品尺寸 | 250 µCi |