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Opal 7 Tumor Infiltrating Lymphocyte Kit

The Opal Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact FFPE tissue sections.







The Opal 7 Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact formalin-fixed, paraffin-embedded tissue sections.

The kit includes all critical workflow reagents to enable 6-plex fluorescent immunohistochemistry: primary antibodies, antibody diluent, fluorescent IHC detection reagents, Spectral DAPI, and antigen retrieval buffers. This kit was configured and validated for multispectral imaging on the Vectra and Mantra Systems. Contains enough reagents for 6-plex immunostain of 50 slides.

  • Optimized panel for assessment of TILs in intact FFPE tissue
  • Shortest path to results
  • Part of the Phenoptics workflow for immunophenotyping of solid tumors

免责声明:  For research use only. Not for use in diagnostic procedures.


检测目标 CD4,CD8,CD20,FOXP3,CD45RO,panCK
自动化兼容 No
检测方法 MSI, Fluorescence
荧光基团 Opal 520,Opal 540,Opal 570,Opal 620,Opal 650,Opal 690
产品品牌名称 Opal
包装量 1.0 per pack
Target Species Human
产品尺寸 50 slides



所有 (22)
资源类型 文件名 文件格式
产品手册 Brochure: Phenoptics Portfolio PDF  2 MB
数据单表 Data Sheet: Opal 7 Tumor Infiltrating Lymphocyte Panel Kit TDS PDF  255 KB
单页 Flyer: Phenotype and Visualize with Opal Kits PDF  3 MB
产品信息 Product Info: Let's Rid the World of Ribbons - Infographic PDF  822 KB
Opal Multiplex IHC Assay Development Guide Guide: Opal Multiplex IHC Assay Development 指南
Phenoptics Research Solutions e-book Phenoptics Research Solutions E-Book 电子书
Scientific Paper Publication: Linch, Stefanie N., et al. "Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice." Proceedings of the National Academy of Sciences 113.3 (2016): E319-E327 链接
Scientific Paper Publication: Miecnik, Bernhard, et al. "The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis." Science translational medicine 8.327 (2016) 链接
Scientific Paper Publication: Esbona, Karla, et al. "COX-2 modulates mammary tumor progression in response to collagen density." Breast Cancer Research 18.1 (2016) 链接
Scientific Paper Publication: Feng, Zipei, et al. "Multispectral Imaging of T and B Cells in Murine Spleen and Tumor." The Journal of Immunology 196.9 (2016): 3943-3950 链接
Scientific Paper Publication: NEJM: Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma 链接
Scientific Paper Publication: Novartis Genoptix Shows Multiplexed IHC Test Better Predicts Immunotherapy Response 链接
Scientific Paper Publication: Woods, Katherine, et al. "Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma." Journal for immunotherapy of cancer 4.1 (2016) 链接
Scientific Paper Publication: Huang, Fangjin, et al. "Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET." The Journal of Pathology: Clinical Research (2016) 链接
Scientific Paper Publication: NEJM: PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma 链接
Scientific Paper Publication: Ören, Bilge, et al. "Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis." The Journal of Pathology (2016) 链接
Scientific Poster Poster: Optimization Strategy For Fluorescence Multiplex Immunohistochemistry Tissue Staining 链接
Scientific Poster Poster: Automate Your Complete Cancer Research Workflow with Phenoptics™ 链接
Support Pages Application Support Knowledgebase: Opal Multiplex IHC Assay FAQs 链接
网络研讨会 Webcast: The Beginning of the End - Immunoprofiling Coming of Age 链接
网络研讨会 Webinar: Untangling the tumor microenvironment: Illuminating the complex interactions and functions of immune cells 链接
网络研讨会 Webinar: Using multiplexed IHC to Effectively Navigate the Hidden Clues of the Immunological Microenvironment 链接