PerkinElmer
check quantity

SB-269970, [3H]

Tritiated SB-269970. SB-269970 is believed to act as a selective serotonin 5-HT7 antagonist, or possibly an inverse agonist.

部件号 NET1198U250UC
立即购买

请输入有效的数量

请登录后再添加至收藏夹

购物车为空

项目已成功添加到购物车

詳情 信息

SB-269970 is believed to act as a selective serotonin 5-HT7 antagonist, and is used to study receptors in the hippocampus and thalamus regions of the brain. The 5-HT7> receptor beongs to a group of GPCRs and is possibly involved in autism and neuropsychiatric disorders.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

规格

检测方法 Radiometric
标签位置 Specifically Labeled
产品品牌名称 NEN Radiochemicals
放射性同位素 H-3
放射性核素 3H
受体类型 5-Hydroxytryptamine
运输条件 干冰
特殊订购信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
产品尺寸 250 µCi