PerkinElmer

肿瘤免疫治疗与免疫学

OF

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

LANCE Detection Kit
LANCE Detection Kit

Kits and Reagents for Immuno-Oncology Research

Targeting immune checkpoint inhibitors, such as PD-1, PD-L1, and CTLA-4, has become pivotal in immunotherapy research, and so have monoclonal antibodies (mAbs), whether naked or conjugated with a chemotherapy agent or radioactive particle. Another area of active investigation is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically programmed to attach to proteins on the surface of cancer cells. We offer a number of reagent technologies, radioactive and non-rad, for detection of key immuno-oncology targets.
Vectra 3 200 slide
Vectra 3 200 slide

Instrumentation for Immuno-Oncology Research

With our full suite of immuno-oncology products and solutions––including instrumentation and software for in vitro, ex vivo and in vivo models––we enable rapid and targeted discoveries in cancer immunotherapy.
Contract Research Services for Phenotyping In Situ
Contract Research Services for Phenotyping In Situ

Contract Services for Immuno-Oncology Research

Looking for an assay that’s not commercially available? Ask us about our custom services for immuno-oncology research including custom labeling of biomolecules, full assay development and transfer, and tissue imaging and analysis.

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"肿瘤免疫治疗与免疫学" 1-50316 产品与服务

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Vectra Polaris with monitor

Vectra Polaris 全自动定量病理成像系统

Vectra® Polaris 全自动定量病理成像系统,将光谱成像与自动化的玻片扫描融为一体,可以在组织原位更好地观察、分析和定量统计不同表型的免疫细胞,兼容HE, IHC, IF等不同染色方式以及FFPE和TMA样本。
Quantum GX2 microCT imaging system

Quantum GX2 microCT成像系统

应用领域涉及骨、肿瘤、心血管和肺部等疾病研究。Quantum GX2 micro CT成像系统模式灵活,兼容离体样本、小鼠、大鼠及兔子等多种物种;具备快速、低剂量的扫描模式,适合对活体动物进行长时程研究;具备高分辨率成像特点,能够对离体样本进行高分辨扫描。 Quantum GX2 microCT卓越的性能让您不仅得到图像,而是更深入的理解疾病模型。
FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
Vectra image

Vectra 3.0 Automated Quantitative Pathology Imaging System

Vectra® 3 定量病理成像系统,准确探测和策略弱信号以及重叠的信号,适用于福尔马林固定石蜡包埋的组织切片或组织芯片,兼容HE,IHC,IF等染色方式。
G8 PET/CT benchtop scanner for preclinical imaging research

G8 PET/CT 成像系统集

PerkinElmer 公司最新研发的 G8 PET/CT 二合一成像系统集成了高灵敏度 PET 成像及快速、低剂量 microCT 成像,使研究者在进行功能或代谢研究的同时,获取结构性图像数据。
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III 小动物活体成像系统

IVIS® Lumina III是PerkinElmer最新推出的第三代高灵敏度多光谱小动物活体光学二维成像平台。
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT 小动物活体成像系统

IVIS® Spectrum CT是全球顶尖的小动物活体三维光学/CT二合一成像系统。
IVIS Spectrum In Vivo Imaging System

IVIS Spectrum 小动物活体成像系统

IVIS® Spectrum 小动物活体光学成像系统是全球首台同时具备生物发光、荧光、化学发光及切伦科夫二维/三维成像功能的系统,代表了目前活体光学成像技术的最高水平。
Mantra benchtop

Mantra 定量病理分析平台

Mantra 定量病理分析平台配合inForm软件,可以观察、分析、定量统计不同的免疫细胞表型和数目,助力肿瘤免疫研究。
Opera Phenix HCS Systems

Opera Phenix 高内涵系统

Opera Phenix™高内涵系统是目前最受期待的高内涵共聚焦技术方案。依赖将近20年的顶尖高内涵产品opera高内涵成像系统积累的丰富成像和应用经验,新一代的opera phenix系统系统专为高内涵表型筛选以及复杂的疾病模型量身打造,例如活细胞、原代细胞,细胞微组织。
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS 小动物活体成像系统

IVIS® Lumina XRMS III是PerkinElmer最新推出的二维多模式活体成像系统,具备最高灵敏度的生物发光、多光谱荧光、放射性同位素和X光活体成像功能。
Operetta CLS HCS System

Operetta CLS 高内涵系统

Operetta CLS™ 系统帮助您探索常规实验与复杂创新实验中的生物学信息。通过一系列创新技术的有机结合,Operetta CLS™ 同时满足精细细胞细节成像对高速、高灵敏度、高分辨率检测多方面的需求。同时,凭借功能强大的Harmony 4.5版软件,Operetta CLS™ 可帮助您发现并定量细微的细胞表型改变。
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT 小动物活体成像系统

IVIS® Lumina LT是PerkinElmer最新推出的第三代高灵敏度小动物活体光学二维成像平台。
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
AlphaLisa Analyte 2

PIP Collagen (human), lyophilized (LANCE)

PIP collagen standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra PIP Collagen TR-FRET Detection Kit, but can also be ordered separately.
AlphaLISA immunoassay kits

TNFα (cynomolgus) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for cynomolgus TNFα enables the quantitative determination of cynomolgus tumor necrosis factor alpha in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.  

PSA (human) AlphaLISA Detection Kit

The AlphaLISA® Human Prostate-Specific Antigen (PSA) Detection Kit is designed for detection and quantitation of human PSA in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. PSA is also known as Kallikrein-related peptidase 3 (KLK3).
AlphaLISA immunoassay kits

Perlecan (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human perlecan enables the detection and quantitation of human perlecan (endorepellin) in human serum and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay showed no cross reacitivity to vimentin, fibronectin, nidogen-1, laminin, or collagen I.
Amplification Diluent

TSA Fluorescein Reagent Pack

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
AlphaLisa Analyte 2

CTLA-4 (human), lyophilized (AlphaLISA)

Human CTLA-4 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human CTLA-4 Detection Kit, but can also be ordered separately.
Opal 7-Color Automation IHC Kit 50 slides - NEL801001KT

Opal Automation IHC Kit 50 Slide

Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed. The Opal 4-Color Automation Immunohistochemistry Kit is designed for use on the Leica Biosystems BOND RX, and is configured and validated for imaging on the Vectra® and Mantra systems. This kit contains reagents to stain 50-slides at the recommended dilution ratio.

TSA Plus Cyanine 5.5

TSA® Plus Cyanine 5.5 (Cy5.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5.5 in the localized area of the probe or antibody.

EGFR (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human EGFR Detection Kit is designed for detection and quantitation of human Epidermal Growth Factor Receptor in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Protein

PD-1 (human), lyophilized (LANCE)

Human PD-1 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human PD-1 TR-FRET Detection Kit, but can also be ordered separately.
Protein

COX-2 (human), liquid (LANCE)

Human COX-2 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human COX-2 TR-FRET Detection Kit, but can also be ordered separately.

BCL-2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human BCL-2 Detection Kit is designed for detection and quantitation of human Bcl-2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
AlphaLISA immunoassay kits

Collagen IV (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human collagen IV enables the quantitative determination of collagen IV in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
AlphaLISA immunoassay kits

CD117 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CD117 enables the quantitative determination of human CD117 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
AlphaLISA immunoassay kits

Mesothelin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human mesothelin enables the quantitative determination of human mesothelin (CAK1, ERC) in serum, buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
AlphaLISA immunoassay kits

p62 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for p62 enables the quantitative determination of p62 in human cell lysates using a homogeneous AlphaLISA assay (no wash steps).

EGF (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human EGF Detection Kit is designed for detection and quantitation of human epidermal growth factor in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
AlphaLISA immunoassay kits

BCL-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for BCL-2 enables the detection and quantitation of human BCL-2 in serum, buffered solution, or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). This kit is not cross reactive with mouse Bcl-2.
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.

HLA-E (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human HLA-E enables the quantitative determination of human MHC class I antigen E (HLA-E) in buffered solution, cell culture supernatants, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
AlphaLISA immunoassay kits

MMP-12 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP-12 enables the detection and quantitation of human matrix metalloproteinase-12 in serum or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). The kit was designed to detect both MMP12 and pro-MMP12.

EGFR (human) AlphaLISA Detection Kit

The AlphaLISA® EGFR Detection Kit is designed for detection and quantitation of human Epidermal Growth Factor Receptor (EGFR) in cell culture media, human serum, and other sample types using a homogeneous (no-wash steps, no separation steps) assay.

PSMA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PSMA enables the quantitative determination of human prostate specific membrane antigen (PSMA) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

TSA Plus Cyanine 3.5

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.
PerkinElmer

Membrane Target Systems: Adenosine A3 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

Alpha-1 Anti-Trypsin (A1AT) (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human A1AT enables the detection and quantitation of human A1AT (hA1AT) in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with Human Anti-thrombin and mouse A1AT.
AlphaLISA immunoassay kits

PTEN (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PTEN enables the detection and quantitation of human PTEN in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps). Other species of PTEN were not tested, but detection is expected with mouse and rat PTEN due to >99% sequence homology.
In vivo Fluorescent Agents

ProSense 680 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 

MMP-9 (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Matrix Metalloproteinase-9 (MMP9) Detection Kit is designed for detection and quantitation of murine MMP9 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit was designed to detect both MMP9 and pro-MMP9.
Bioluminescent Oncology Cell Lines - Bioware

Bioware® Brite Cell Line HCT116 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
AlphaLisa Analyte 2

CD28 (human), lyophilized (AlphaLISA)

Human CD28 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human CD28 Detection Kit, but can also be ordered separately.
Receptor-expressing cell lines

ValiScreen Adenosine A3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
In vivo Fluorescent Agents

MMPSense 645 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
Bioware Bioluminescent Oncology Cell LInes

Bioware® Brite Cell Line 4T1-Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.

"肿瘤免疫治疗与免疫学" 1-50316 产品与服务

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