PerkinElmer

Cancer Research Solutions

通过不断探索癌症的复杂细节研发更有效的肿瘤治疗方案。我们丰富的癌症研究相关产品帮助您实现体外、体内、组织水平检测、成像以及数据分析。

  • 通过成像和分析组织切片样本进一步了解肿瘤微环境,探索新的疾病亚型和新型靶点。
  • 使用我们的小动物活体设备从分子、功能、解剖学角度出发研究动物模型对治疗的响应。
  • 通过我们的高内涵筛选系统和信息化解决方案获取更深入的肿瘤细胞表型信息。
  • 通过我们的多功能酶标仪进行多种实验和试剂快速灵敏的检测和评估关键的肿瘤标志物。
  • 我们提供自动化解决方案帮助您提升实验效率,进一步提高研发速度。

Cancer Genomics

Cancer genomics aims to understand the genetic basis by which tumors proliferate and evolve under selection by its microenvironment, the immune system, and therapeutic intervention. Identifying the genetic and epigenetic changes at the root of cancer has improved our understanding of its biology and lead to new methods of diagnosing and treating the disease.

For research use only. Not for use in diagnostic procedures.

表观遗传学

To help unravel the complex biology of epigenetics, we provide a suite of enabling reagents and technologies that shorten assay development time and accelerate drug discovery for key epigenetic targets. Our epigenetics solutions – from validated assays to detection methods for readers, writers, and ...

Next-generation sequencing

It is a powerful tool used to analyze molecular targets for cancer diagnosis, monitor disease progression, and identify the mechanism of drug resistance.

Gene editing and modulation

Enables researchers to understand disease mechanisms and cancer vulnerabilities at the genomic level. Whether looking at permanent or temporary changes to gene expression, our cell lines, reagents, libraries, and services can be tailored to you.

Single-cell RNA sequencing

Provides transcriptional profiling of individual cells, enabling researchers to understand what genes are expressed, in what quantities, and how they differ within a biological sample – all at the single-cell level.

Cancer Cell Biology

Cancer cell biology investigates the underlying differences between normal cells and cancer cells and elucidates basic mechanisms that drive the development and behavior of tumors. Understanding this biology, and the fundamental processes governing transformation, is critical for identifying molecular targets for therapeutic or preventive intervention.

蛋白质检测

Detect and quantitate proteins across a variety of sample types. We offer a broad range of products including traditional western blotting reagents and consumables, radioimmunoassay (RIA), ELISA, and ELISA alternative assays, tissue imaging systems and immunohistochemistry reagents, and innovative m ...

GPCR

G蛋白偶联受体(GPCR)是结构变化多样的一大类蛋白膜受体,包括:β1和β2肾上腺素能受体、多巴胺能受体和胆碱能受体。我们可提供G蛋白偶联受体研究所需的所有先进检测分析设备。 以及多种靶标Gs-、Gq-和Gi-偶联受体的实验试剂。 我们产品还包括: 荧光、发光或吸收光检测所需的可调焦GPCR细胞成像仪和液体工作站; 经优化的GPCR细胞水平检测平台 多样检测试剂——GPCR稳定表达细胞系、冷冻即用型GPCR细胞株及细胞膜制品,以及放射性配体等 我们完备的产品组合能够满足GPCR研究的全部需求。您可借助以上仪器及试剂产品进行如下GPCR的研究应用: GPCR通路激活研究:细胞内钙流、cAMP、磷 ...

Protein-Protein Interaction Research

Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interac ...

激酶

Cancer, diabetes, and Alzheimer’s research can benefit from the study of phosphorylation and protein kinase activity. Because of their role in signal transduction, kinase activity detection and characterization is significant for drug discovery. We offer a range of end-point and real-time kinetic pr ...

Cell Counting & Viability

Assessment is vital for any cell-based assay. It’s also critical to assess the potency of any new anti-cancer therapeutic. Our image cytometers and cell counters are designed to enhance your productivity with simple acquisition and analysis workflows.

Immuno-Oncology

Immuno-oncology (I-O) is an especially exciting area of research because it harnesses the body’s immune system to fight cancers. However, to develop new ways to improve immune cell activity, you need a deep understanding of the complex relationship among tumor biology, tumor microenvironment, and the immune system.

Our wide range of tools helps support and advance your I-O research, redefining and developing tailored, life-changing immunotherapies to fight cancer.

Cytokine Research Reagents

Cytokines regulate several physiological and pathological roles including innate immunity, acquired immunity, and many inflammatory responses. PerkinElmer offers the full range of cytokine assay kits, from interleukins, interferons (IFN), and chemokines to TNF and lymphokines, in an easy and ready-t ...

Protein-Protein Interaction Research

Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interac ...

Drive Cancer Discovery With BioLegend

Our extensive range of cutting-edge technology to help you isolate, phenotype, and characterize target cell populations. With the support of our technical teams, you are empowered to create complete solutions for immuno-oncology research.

Biodistribution monitoring

Biodistribution monitoring of immune cells within complex biological systems aids therapeutic development by quantifying efficiency and viability. Our in vivo solutions provide the sensitivity to support tracking of immune cells with anatomical context.

Immune cell potency

Immune cell potency assessment is critical to revealing the compound mechanism of action and fine-tuning therapeutic selection. Our imaging systems provide single-cell analysis of immune response characteristics even within 3D models.

Tumor Microenvironment

Imaging tumors within their microenvironments provides insights into complex interactions between cancer cells and surrounding immune cells, fibroblasts, signaling molecules, and extracellular matrices. Recent advances in tumor biology reveal these interactions control tumor growth and the development of metastasis, providing new points for therapeutic intervention.

3D Cell Model Workflows

The journey to discovering novel targets starts with building a deep understanding of the underlying biology. To achieve this, researchers are increasingly looking to 3D cell cultures, microtissues, and organoids to bridge the gap between 2D cell cultures and in vivo animal models. 3D models provide ...

为癌症研究提供小动物影像学解决方案

研究癌症生物学并评估体内治疗效果。 小动物影响学因其独特的优势日益成为癌症研究的一种重要手段。利用小动物成像,研究人员可在体内水平针对癌症进行非侵入性检测和分析。 无论是监测肿瘤生长和进展、血管生成、转移和进行药物疗效及毒理学研究,还是帮助加深了解肿瘤生物学,我们提供的工具能够帮助您实现下个癌症研究突破。 仅供科学研究使用。不适用于临床诊断。 用于癌症研究的体内影像流程

Tissue microenvironment

Comprises of proliferating tumor cells, stroma, blood vessels, infiltrating inflammatory cells, and a variety of tissue cells. Our antibodies enable you to spatially phenotype every cell, linking cell biology to in vivo function and pathogenesis.

Precision Medicine

Every cancer is unique, from their genetic makeup to their microenvironment. Individually tailored therapy relies on understanding both the underlying genetics and functional responses of cancers throughout the course of treatments to stay one step ahead of any resistance.

Our complementary approaches to screening patients’ molecular profiles enable you to identify the right drug – for the right patient, at the right dose, and at the right time.

For research use only. Not for use in diagnostic procedures.

用于精准医疗与免疫疗法的基于图像的筛选

Functional drug testing patient-derived cancer cells are used to match individuals to the right therapies for them. Our high-content imaging systems help you tease apart subtle, yet crucial phenotypic differences within ex vivo cultures.

Next-generation sequencing (NGS)

Analysis of the heterogeneous genetic composition of a tumor can reveal patients with oncogenic driver mutations. Our automated NGS workflows allow multiple genes to be analysed simultaneously with enough depth to detect minor allele frequencies.

Biomarker Discovery

Liquid biopsies provide unique molecular characteristics of an individual's cancer. Our automated workflow covers all the steps in the process, from plasma extraction to library preparation, for consistent high-quality, error-free results.

Data Integration

Streamlining in-house data with clinical trial information and publicly available facts – is key to expedite improved therapeutic outcomes. Our Signals ™ platform empowers researchers to accelerate the realization of precision medicine.

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