Discover how PerkinElmer high-content screening solutions can benefit your research in both new and established applications. From everyday assays to the most demanding imaging and high-throughput screening applications, our high-content screening systems deliver the right combination of advanced optics and software features to help you glean more physiologically relevant information from your assays.
Due to their size 3D tissues pose characteristic challenges to any imaging system but benefit greatly from confocal imaging.
HCS assays are at the heart of phenotypic drug discovery: a strategy which implies little foreknowledge of the mode-of-action of potential drug candidates and relies on physiologically relevant and predictive model systems of the disease in question.
Cell Painting is a prominent example of a phenotypic assay and a powerful application of high-content screening technology. It combines cell and computational biology to gain a deeper understanding of the impact of genetic or exogenous perturbagens, with the aim of identifying potential new therapeutics, investigating human gene function, or the assessment of environmental toxicants.
Live cell imaging is the study of living cells using images acquired from imaging systems such as microscopes and high content screening systems.
Cell signalling, physiology and function can all be studied using a high-content analysis approach, and PerkinElmer offers a range of solutions to enable you to develop, perform and analyze your cellular assays with ease. Learn more about the many types of phenotypic assays that can be run in a high-content format and find further details in our application notes.
High-content analysis (HCA) has expanded into all corners of life science since its beginnings in drug discovery and is now used widely in a diverse range of scientific research areas including oncology, neuroscience, infectious disease, and toxicology, to name just a few.