PerkinElmer’s selection of reagents for cell free DNA isolation and analysis address the challenges facing laboratories today, from low input samples, labor constraints, and complex and expensive analyses to address all laboratory needs.
For research use only. Not for use in diagnostic procedures.
The Vanadis platform is a highly automated non-PCR, non-NGS based cell-free DNA analysis platform enabling cost-effective quantification of targeted chromosomes. Vanadis reagents and consumables were optimized to streamline the workflow and improve your lab efficiency.
The isolation of cfDNA is a huge challenge due to low concentrations, instability, and small fragment sizes of 50 - 200 bp and therefore precise and reliable cfDNA purification workflows are required. Based on the unique chemagen Technology using M-PVA Magnetic Beads, PerkinElmer has developed the chemagic™ cfDNA kits to isolate cfDNA from 0.5 - 5 ml fresh and frozen plasma derived from EDTA, citrate or other common collection tubes with minimal hands-on time using the chemagic™ instruments.
The automated sample processing by the chemagic™ instruments excludes cross contamination and ensures safe handling of infectious sample material.
The NextPrep-Mag™ Urine cfDNA Isolation kit is designed for extracting cell-free DNA (cfDNA) for constructing NGS libraries from urine, using a fast, magnetic bead-based format requiring minimal hands-on time. The isolation procedure, which can be completed in approximately 30 minutes, includes an initial lysis and DNA binding step, wash steps, and elution of cfDNA from the magnetic beads.
The NEXTFLEX® Cell Free DNA-Seq Kit 2.0 can produce libraries from 10 ng of cell free DNA in only two hours. This low-input library preparation kit delivers high coverage quality and reduced bias for Illumina® sequencing applications.