Infectious Disease Research

Understanding host-pathogen interactions on a molecular, cellular or organism level is the basis for developing effective new treatments. To achieve physiological relevant results, today’s infectious disease research moves towards more complex disease models such as co-cultures or organoids that better resemble in vivo biology. Whether you want to analyze infection of cellular models or in vivo models, or study protein:protein interactions and identify PPI inhibitors, we provide the reagents, instruments and software you need to enable these applications.

When a pathogen infects the human body, a battle ensues between the host’s innate & adaptive immune systems and the pathogen’s virulence mechanisms and factors. Pathways such as MAP kinase, JAK/STAT, and NFκB play a central role in the antiviral immune response along with ligands such as IL-6, TNFα, and the INFs (-γ, -α, -β, and -λ). PerkinElmer offers a wide range of reagents, detection and imaging instruments enabling to study the antiviral immune response both in vitro and in vivo.

Antimicrobial research and drug discovery requires sensitive and reliable technologies to detect microbial growth and measure antimicrobial effects. We provide solutions to measure bacterial growth or viral titers, perform target-based, high-throughput drug screens or phenotypic screening and characterize bacterial phenotypes for antimicrobial resistance research using high-content analysis.

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Continued discovery of new antiviral medications and vaccines is important for global human health, particularly as new viruses such as the novel Coronavirus or novel Influenza viruses can emerge quickly. We offer solutions for measuring virus neutralization, antiviral compound effects, antiviral immune response or for studying cytokine storm, which is associated with COVID-19.

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