PerkinElmer

Inflammation Assays

Inflammation occurs when tissues are injured by bacteria, trauma, toxins, heat, or other causes. Both C-Reactive Protein (CRP) and Procalcitonin (PCT) are released into the bloodstream during inflammation, can be used as systemic inflammatory markers.

CRP is one of the acute phase reactive proteins. In inflammation, infection and tissue damage, CRP is mainly produced by the liver under the stimulation of cytokines. Conventional CRP can be used to evaluate infection, tissue damage and inflammatory diseases. High-sensitivity CRP (hs-CRP) can be used as an auxiliary means to identify the risk of cardiovascular disease, in conjunction with the traditional clinical diagnosis methods of coronary syndromes. And it is also useful as an indication of recurrence of acute coronary syndrome or coronary artery disease.

PCT is the precursor peptide of the mature hormone calcitonin, which is released by multiple tissues under the stimulation of infection and inflammation. PCT has a good correlation with infection and sepsis, which is used for the differential diagnosis of bacterial and non-bacterial infections, differential diagnosis of sepsis, guiding the use of antibiotics and testing the effects of treatment, and prompting the prognosis of the disease. When a bacterial infection occurs, the PCT concentration increases and is related to the severity of the disease. After the infection is controlled, the PCT value decreases.

Because CRP and PCT are nonspecific, they can be used to identify a generalized inflammatory state and can aid in the differential diagnosis.

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  • Chemiluminescence immunoassay (CLIA) (2)
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  • SuperFlex Automated Chemiluminescence Analyzer

    The SuperFlex Automated Chemiluminescence Analyzer is CE-IVD marked and intended for in vitro diagnostic use. It delivers ultra-sensitive detection of small biological molecules using labeled antibodies and antigens in serum, plasma and whole blood. Twelve independent channels allow it to process up to twelve assays and 24 sample position randomly separately or simultaneously. With hands-free processing of samples, up to 48 - 60 samples to be processed per hour in 5 - 15 minutes depending upon assay.
  • PerkinElmer

    SuperFlex All in One CRP Kit

    The SuperFlex All in One CRP Kit is intended for the in vitro quantitative determination of C-reactive protein concentration (including hypersensitive C-reactive protein [hs-CRP] and C-reactive protein [CRP] in human serum, plasma or whole blood samples (venous blood or peripheral blood) using the SuperFlex Automated Chemiluminescence Analyzer.

    All information presented is for informational purposes only and is not intended for medical advice. Products may not be licensed in accordance with the laws in all countries, such as the United States and Canada. Please check with your local representative for availability.

  • SuperFlex Procalcitonin Kit

    The SuperFlex PCT Assay is intended for the in vitro quantitative determination of procalcitonin (PCT) in human serum, plasma or venous blood using the SuperFlex Automated Chemiluminescence Analyzer.

    All information presented is for informational purposes only and is not intended for medical advice. Products may not be licensed in accordance with the laws in all countries, such as the United States and Canada. Please check with your local representative for availability.

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