PerkinElmer

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Simplify the development of your assays and the calculation of your results using our radioligands, receptor-transfected cell membranes, and cell lines for radioligand binding applications.

Because radioligands can be directly detected, there is no need to generate intermediate antibodies against your target. Eliminating these antibodies also eliminates the need to optimize an antibody titer and reduces your total assay time by skipping intermediate incubation steps.

You’ll find our receptor-ligand binding reagents and related products perfect matches for all of your receptor binding studies.

 

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"受体配体结合" 1-50532 产品与服务

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MICROBETA FILTERMAT-24 孔细胞收集器

速度快、操作简单是 Filtermate 收集器的主要优势。FilterMate 系统的整个操作过程都很简便。若需要更多信息,请点击产品上的选项卡。

MICROBETA FILTERMAT-96 孔细胞收集器

速度快、操作简单是 Filtermate 收集器的主要优势。FilterMate 系统的整个操作过程都很简便。

OMNIFILTER-96 孔细胞收集器

速度快、操作简单是OmniFilter收集器的主要优势。
LabChip EZ Reader

酶动力学读板仪

酶动力学读板仪以更低的时间和经费成本,帮您的实验室更快的发现最有潜力的候选化合物。

UNIFILTER-96 孔细胞收集器

速度快、操作简单是Unifilter收集器的主要优势。

UNIFILTER-96 孔细胞收集器 SS

速度快、操作简单是Unifilter收集器的主要优势。

UNIFILTER-24 孔细胞收集器

速度快、操作简单是Unifilter收集器的主要优势。
Receptor-expressing cell lines

ValiScreen Adrenergic beta 2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Triiodothyronine, ([125I]-T3), Specific Activity: 1080-1320 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Glucagon, Receptor Grade, [125I]

Glucagon, labeled with 125I. This product is receptor grade, and was developed for use in receptor binding assays. Glucagon binds and activates glucagon receptor, a GPCR that is a potential drug target for diabetes, hyperplasia, and pancreatic disorders.
PerkinElmer

Streptavidin PS Imaging Beads 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.

Triiodothyronine, ([125I]-T3), Specific Activity: 135-165 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
PerkinElmer

Membrane Target Systems: Neurokinin NK2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
PerkinElmer

Histone 4 Acetylated Peptide, for LabChip EZ Reader

Fluorescently-labelled Histone 4 Peptide (Acetylated) for Epigenetic Assays (Enzyme inhibiton, target discovery, lead optimization)

Neurotensin, [125I]Tyr3]

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.
PerkinElmer

Membrane Target Systems: Adenosine A1 (rat) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with rat adenosine A1 receptor, 400 units.
PerkinElmer

STREP PVT SPECIAL 25 X 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.

(+)-Pentazocine, [Ring-1,3-3H]

(+)-Pentazocine radioligand tritiated at the 1,3 position on the ring. Pentazocine is a synthetic opioid shown to bind sigma 1 receptor.

MDL105,519, [3H]

Tritiated MDL 105,519. MDL 105,519 acts as a potent and selective antagonist at N-methyl-D-aspartate (NMDA) receptors.
PerkinElmer

PEI PS Imaging Beads 50 MG

SPA imaging beads coated with polyethyleneimine (PEI) to decrease non-specific binding. These beads are commonly used in receptor binding assays.
PerkinElmer

Anti-rabbit PVT 500 MG

Anti-rabbit-coated SPA beads, for capturing rabbit IgG antibodies in proximity-based radiometric scintillation assays.

Insulin (human, recombinant), [125I]

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
PerkinElmer

Membrane Target Systems: Adrenergic alpha 2B (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

Goat anti-rabbit IgG, [125I]

Anti-rabbit immunoglobulin G (IgG), labeled with 125I. I-125 labeled anti-rabbit IgG can be used as a tracer to capture rabbit IgG antibodies in radioimmunoassays (RIAs).
PerkinElmer

Membrane Target Systems: Vasopressin V2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Vasopressin V2 receptor, 400 units.
PerkinElmer

ProfilerPro Kinase Peptide Substrate 4, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 4 for kinase assays (inhibiton, target discovery, lead optimization)

Thyroxine, ([125I]-T4), Specific Activity: 1080-1320 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.

Ghrelin (human), [His[125I]]

Ghrelin, labeled with 125I. Ghrelin is a peptide that regulates appetite and energy, and binds the ghrelin/growth hormone secretagogue receptor (GHS-R).
PerkinElmer

Membrane Target Systems: Histamine H2 (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human Histamine H2 receptor, 400 units.
PerkinElmer

Membrane Target Systems: Adenosine A3 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
AlphaLISA immunoassay kits

FcRn (human) AlphaLISA Binding Kit

The AlphaLISA human FcRn binding kit is designed for the detection of binding between FcRn and human IgG using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
PerkinElmer

Membrane Target Systems: Melanocortin MC5 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Melanocortin MC5 receptor, in HEK-293 cells.
PerkinElmer

Protein A YSI 500 MG

Protein A-coated SPA beads, for capturing antibodies in proximity-based radiometric scintillation assays.

CGRP (human), [125I]

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.

Mazindol, [4`-3H]-, 250µCi (9.25MBq)

Mazindol, tritiated at the 4' position. Mazindol has been shown to block dopamine (DAT), serotonin (SERT), and norepinephrine (NET) transporters.
PerkinElmer

LabChip ProfilerPro Separation Buffer (400 ml) including Coating Reagent 8, for EZ Reader

Separation buffer containing coating reagent 8 (CR8), a positively-charged additive that binds the silanol groups of the glass channels in the LabChip multi-sipper chip (the glass is negatively-charged) to neutralize the charge. Non-specific interaction of substrates and products that are highly positively charged, or substrates with sequences containing repeats of a positive charge, will be reduced with this separation buffer.

2-Methylthio ADP, [β-33P]-, 10mM Tricine (pH 7.6)

33P labeled 2-methyl-thio ADP (2-MeS-ADP), labeled on the beta phosphate group. 2-MeS-ADP acts as an agonist at P2Y1, P2Y12, and P2Y13 receptors and is used in platelet aggregation research.
Receptor-expressing cell lines

ValiScreen Prostanoid CRTH2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Streptavidin PVT 150MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
Receptor-expressing cell lines

ValiScreen Chemokine CX3CR1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Gastric Inhibitory Polypeptide (human), [125I]

Gastric inhibitor polypeptide (GIP), labeled with 125I. GIP is a hormone that binds receptors found on beta cells in the pancreas.
PerkinElmer

Streptavidin YSI 250MG YTTRIUM

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
Receptor-expressing cell lines

ValiScreen Chemotactic Peptide C3a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

ValiScreen Muscarinic M2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

ValiScreen Prolactin Rel. Peptide PRRP (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Nociceptin ORL1 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Nociceptin ORL1 receptor, in HEK-293 cells.
Receptor-expressing cell lines

ValiScreen Neuropeptide Y Y2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Orexin A, [125I]

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.
PerkinElmer

Membrane Target Systems: Melanocortin MC3 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Melanocortin MC3 receptor, in HEK-293 cells.

"受体配体结合" 1-50532 产品与服务

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