The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
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When analyzing food and environmental samples, laboratories often need multiple system to get the qualitative and quantitative information on contaminants. But this can result in duplicated sample preparation processes, increased cost of ownership – and suboptimal lab efficiency. Discover the unique ...
在养蜂业中，磺胺类药物是治疗美国和欧洲臭虫病（一种感染蜜蜂的疾病）的最常用抗生素。本应用说明介绍了QSight 200系统如何为蜂蜜中磺胺类药物的分析提供一个非常灵敏和可靠的平台。
本文提出了一种快速、灵敏的LC/MS/MS方法。
继2018年加拿大娱乐性大麻使用合法化之后，大麻产品的质量和安全性受到了极大关注。加拿大卫生部制定了一项监管计划，要求对所有大麻制品进行农药检测。根据该计划，加拿大大麻制品的许可生产商（LPs）必须向独立实验室发送具有代表性的产品样本，以便进行农药筛查和定量分析。本文阐述了利用ESI和APCI两种模式的LC/MS/MS分析大麻花中96种农药的一种稳健和可靠的方法。该方法不仅提供超低的检测限（同等或低于加拿大卫生部监管水平），而且与其他可用方法相比，效率显著提高。只需将LC/MS/MS与ESI和APCI模式结合使用来分析所有96种受管制农药，而无需进行GC/MS/MS和LC/MS/MS分析，为操 ...
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
由于具有选择性高、灵敏度高、适用于多种样品基质中多种化合物的分析等优点，液相色谱-串联质谱法（LC/MS/MS）已成为农药分析的首选方法。本研究采用改进的QuEChERS提取法与LC/MS/MS联用，建立了一种快速、灵敏、选择性好的多残留分析方法，对大米中200多种农药进行了分析。采用QSight®三重四极杆质谱仪中的时间管理MRM™，可为目标分析物多个MRM通道自动分配最佳驻留时间。这不仅节约了方法开发的时间，也提高了数据质量和分析性能，这些在本研究中的大米样品中多农药残留分析结果有具体展示。
塑料是当今全球使用量最多的材料之一。它们已广泛融入现代工业和商业生活方式，几乎对每类产品都做出了不可替代的重大贡献。
您将在本纲要中了解聚合物、塑料、橡胶和先进材料的广泛应用，以及这些应用如何简化您的工作并提升效率。
多环芳烃（PAHs）在烟熏、加热和干燥过程中会污染食品，这些过程会使燃烧产物直接接触到食品。它们还可以通过受污染的空气和水进入食物供应链，并在各种食物链中积累。相关机构制定了相关法规来监测食品中多环芳烃的含量；欧盟对熏鱼和熏制水产品肉中的BaP设定了严格的最大残留限量（MRL）为2µg/kg。在本研究中，海产品采用QueChERS萃取法，然后采用分散固相萃取净化步骤制备。随后，通过超高压液相色谱-三重四极杆质谱仪联用系统对样品进行分析。
真菌毒素是由真菌产生的有毒次级代谢产物，使谷物、玉米和谷类食品特别易受污染。基于这些因素，并考虑到估计有25%农作物有被一些霉菌毒素污染的迹象，许多国家制定了真菌毒素最大限量的监管准则，这不仅是对饲料和谷物，而且对加工食品也有要求。
最近在欧洲召回受污染的鸡蛋引起了对氟虫腈中毒的严重健康担忧。氟虫腈是一种剧毒杀虫剂，用于保护农作物。美国环保署已将氟虫腈列为C组致癌物。在这项研究中，我们描述了一种快速、可靠的分析方法，采用PerkinElmer QSight 200系列LC/MS/MS三重四极杆仪器对氟虫腈及其代谢物进行鉴定。结果表明，该方法具有极佳的回收率、线性、重现性和超高灵敏度。三步法样品制备过程快速简便，LC/MS/MS分析时间可在6分钟内完成，所有分析物的分离度都很高。
QSight-LC/MS/MS分析无需样品制备的葡萄酒中痕量农药。
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
为了保护人类健康，世界各地的监管机构制定了食品中兽药的最大残留水平（MRL）或允许水平。根据监管要求，使用高灵敏度和选择性的技术对四环素进行准确监测对保护人类健康至关重要。本研究提出了一种快速、灵敏的UHPLC/MS/MS方法用于肉类中四环素类抗生素的定量分析。 为了提高实验室生产率，QS Works采用了高通量自动进样器，因为它具有大容量、温控托盘和机械臂，可以长时间无人操作。QS works还允许实验室按顺序运行多达600个样本，从而提高测试实验室的效率。所开发的方法具有良好的灵敏度、线性、回收率、精密度和选择性，用于分析世界上不同监管机构设定的低耐受水平的肉类中的四环素。 ...
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
This application note highlights the LC/MS/MS analysis of PFAS compounds according to the European Union Water Framework Directive 2020/2184. It demonstrates how the PerkinElmer QSight® 420 LC/MS/MS System using a large volume direct injection can determine and quantify the latest 20 PFAS compounds ...
Governing bodies have implemented various directives to monitor acrylamide in drinking water. This also applies in the European Union where the water framework directive and subsequent daughter directives have defined many priority substances, including acrylamide. Compounds chlorate, perchlorate an ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
A simple and sensitive method for the simultaneous determination of plant growth regulators
Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
With routine labs tasked with the analysis of larger and larger target lists, and with greater numbers of samples requiring analysis, we deployed simple sample preparation protocols such as solvent extraction to meet the need of high sample throughput with lower cost. In this work, we demonstrate ho ...
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...
Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...
This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced and widely used in industrial applications and consumer products since the 1950s. The unique physical and chemical characteristics of these ...
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...
聚合物市场充斥着大量工业产品制造商，有着多种不同的处理工艺，但仍面临着类似的挑战。 如为了实现产品高质量并降低成本，在竞争中领先一步，他们面临着越来越大的压力。
