PFAS
Per- and Polyfluoroalkyl substances (PFAS) are a group of industrial chemicals that include such compounds as PFOA and PFOS, among many others. Their fluorine-carbon bonds are extremely stable, making them highly resistant to environmental degradation and earning them the nickname ‘forever chemicals’ due to their longevity.
PFAS monitoring is now a critical requirement, not only to keep up with ever-evolving testing regulations, but to ensure the safety of our planet. Many studies have demonstrated the negative impact of PFAS on both environmental and human health, with findings linking them to severe health concerns including reproductive and developmental issues, depressed immune response, liver and kidney problems, and even cancer.
As the demand for stringent PFAS testing increases, laboratories conducting PFAS research must examine matrices such as drinking water, food packaging, food stuffs, soil, blood, and tissue samples. Our wide portfolio of PFAS analysis solutions provide testing labs with the support they need for implementing and optimizing workflows, including robust performance with complex matrices, reducing matrix-induced contamination, and increasing uptime.

Specifically tailored to meet EPA requirements for PFAS analysis, Simplicity 3Q software streamlines complex tasks such as calculating the total concentration of PFAS isomers by summing their peak areas. It also enables the calculation of the Hazard Index (HI), a critical requirement under the latest EPA regulations.

Designed to equip new labs with the key consumables needed to begin PFAS analysis, this kit includes PTFE-free upgrade kit, delay and analytical columns. It is the ideal solution for labs looking to quickly set up and meet regulatory testing demands.

For regulatory and contract testing labs performing PFAS analysis that want to achieve compliance, reduce instrument maintenance, increase laboratory efficiency, and futureproof against evolving complex matrix requirements, PerkinElmer LC/MS/MS System provides compliant and robust performance for complex matrices. The StayClean™ Technology helps mitigate ion source contamination while supporting lab efficiencies with uptime from reduced source cleaning.

For laboratories starting or conducting Per- and Polyfluoroalkyl Substances (PFAS) analysis, our field engineers, technical service, and R&D teams are ready to get you up and running quickly, ensuring accurate, reliable results, and maximizing lab productivity. Incorporating ad-hoc services ensures that a laboratory is ready and well-equipped to handle the complexities of PFAS analysis with high precision and reliability.

Hands-on operator training delivered at your facility can quickly train multiple operators simultaneously to keep your labs up and running efficiently . Certified Service Engineers ensure users get up to speed on their instruments quickly with minimum instrument and lab downtime.
PFAS Analysis Spotlight
Resources

Overcoming Typical Challenges for PFAS Analysis to Meet Evolving Regulatory Requirements
Overcoming PFAS analytical challenges is critical for a comprehensive understanding of PFAS toxicities and environmental impacts. This article delves into the p ...
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Mitigation of PFAS in Drinking Water Through Analytical Innovation
Per- and polyfluoroalkyl substances (PFAS) have gained significant attention as an emerging environmental and safety threat in the United States. Since the 1940 ...
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What's in Your Water? PFAS Analysis Explained
Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and ...
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PFAS Analysis Brochure
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis. Our robust and reliable LC/MS/MS systems al ...
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Environmental Testing Solutions
We're committed to accelerating your environmental testing results, whatever your workflow looks like. We do it with turnkey solutions complete with analytical ...
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PFAS Monitoring: How One Scientist is Thinking Ahead for the Environment
Predicting the long-term impact some substances have on human health and the environment is extremely difficult and in some instances we only become aware of ce ...
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Drinking Water Analysis Webinar Series
Emerging contaminants include a variety of different chemical pollutants including pharmaceuticals, personal care products, endocrine disrupting compounds, per- ...
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PFAS in Your Pan? The Hidden Dangers of Scratched Teflon
Teflon-coated cookware has been a staple in kitchens worldwide for decades, valued for its non-stick properties that make cooking and cleaning effortless.
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Overcoming PFAS Challenges - Method Development for Changing PFAS Regulations
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement. Governments around the w ...
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Overcoming PFAS Challenges – Mitigating Matrix-Induced Ion Source Contamination
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
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Overcoming PFAS Challenges - Minimizing Sources of Contamination
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
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Mitigate Interference and Contamination in PFAS Analysis
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS mon ...
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PFAS in Drinking Water - Understanding Methods, Challenges, and Trends
Per- and polyfluoroalkyl substances (PFAS) are of increasing concern. In October 2021, the U.S. Environmental Protection Agency (EPA) announced an action plan f ...

PFAS Health Concerns in Air, Water and Soil
Per- and polyfluoroalkyl substances (PFAS) are stable in the environment and can accumulate over time.
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LC/MS/MS: Analysis of Perfluoroalkyl and Polyfluoroalkyl Substances in Aqueous Samples by EPA Method 1633
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to th ...
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LC/MS/MS: Optimized Approach for the Analysis of Perfluoroalkyl and Polyfluoroalkyl Substances in Aqueous Samples by EPA Method 1633
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regu ...

Analysis of PFAS in Drinking Water by Large Volume Direct Injection Following the EU Drinking Water Directive 2020/2184
This application note highlights the LC/MS/MS analysis of PFAS compounds according to the European Union Water Framework Directive 2020/2184. It demonstrates ho ...
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Improved Throughput for the Analysis of Perfluoroalkyl and Polyfluoroalkyl Substances in Drinking Water by EPA Method 533
Growing health concerns regarding Per- and polyfluoroalkyl substances (PFAS) and their prevalence in consumer goods and the environment indicates a critical nee ...
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A Simple and Sensitive Method for Rapid Determination of PFOA and PFOS in Water Samples by Direct Injection UHPLC/MS/MS
Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced ...
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Analysis of PFAS in Drinking Water with EPA Method 537.1 Using QSight UHPLC/MS/MS
Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) are the two most extensively produced and studied of the per- and polyfluoroalkyl substanc ...
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Analysis of Per- and Polyfluoroalkyl Substances by EPA Method 8327 Using the QSight 220 UHPLC/MS/MS
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fi ...
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Rapid and Sensitive Analysis of 17 Per-and Polyfluoroalkyl Substances in Water by Direct Injection with QSight 420
Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for ...
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Direct Analysis of 17 Perfluorinated Compounds in Water at Low Parts-Per-Trillion Levels by LC/MS/MS Workflow
Perfluorinated compounds (PFCs) have received lots of attention recently due to their resistance to degradation in the environment. Reports of their occurrence ...
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Experience Maximized Productivity for PFAS Analysis Even with Complex Matrices
Analyzing Per- and polyfluoroalkyl substances (PFAS) in complex environmental matrices can often impact laboratories with time consuming sample preparation and ...

Conquering PFAS Compliance with Simplified Implementation and Robust LC/MS/MS Workflows
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS ...
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Accurate and Efficient Analysis of PFAS by EPA Method 1633
Join this webinar for an in-depth discussion on PFAS analysis according to EPA Method 1633, while identifying and mitigating background contamination. EPA Metho ...
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Critical Insights in the Detection of PFAS in our Environment
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
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Microextraction Approaches for Environmental Monitoring of Emerging Contaminants
During the PerkinElmer Global Environmental Sciences Summit, Dr. Emanuela Gionfriddo gave a talk on microextraction approaches for environmental monitoring of e ...
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Water Contaminants: Analysis of PFAS Using LC/MS/MS Technology
Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and ...
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Determination of Emerging Contaminants in Water by LC-MS/MS
Emerging contaminants in water continue to be an environmental concern. They include categories of chemicals such as pharmaceuticals and personal care products ...
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What’s in your Water? Monitoring of PFAS in Drinking Water According to EPA Method 537.1
Growing environmental and health concerns about Per- and Polyfluoroalkyl Substances (PFAS) have led to stricter and more extensive regulations of these substanc ...
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Optimizing Workflow and Efficiency in the Analysis of Emerging Contaminants, Including PPCPs and PFAS
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in ...
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PFAS in Air, Water, and Soil: Unraveling the Silent Threat
If you needed one more reason to think about the long-term dangers of per- and polyfluoroalkyl substances, known as PFAS, this could be it: the European Environ ...
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5 Steps to Choosing a PFAS Testing Lab
In 2023, the U.S. EPA’s Fifth Unregulated Contaminant Monitoring Rule (UCMR 5) will go into effect, requiring all public water systems (PWS) serving more than 3 ...
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New Regulations to Monitor Forever Chemicals in the Environment
Since their development in the 1940s, PFAS (per- and polyfluoroalkyl substances) have been utilized in industrial applications due to their chemical stability, ...
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Q&A: Environmental PFAS – the “Forever Chemical” and EPA Method 537.1
The presence of per- and polyfluoroalkyl substances (PFAS) in products used every day by millions of people is a growing cause of concern among both consumers a ...
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PFAS Test Kits
PFAS consumables testing kits offer laboratories a convenient, standardized, and reliable solution for accurate pre- and polyfluoroalkyl substances (PFAS) testi ...
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